Literature DB >> 21780164

Can maximum urethral closure pressure (MUCP) be used to predict outcome of surgical treatment of stress urinary incontinence?

Neil Harris1, Lucy Swithinbank, Samih Al Hayek, Qian Yang, Paul Abrams.   

Abstract

AIMS: The outcome of surgery for stress urinary incontinence (SUI) can be unpredictable. Urethral pressure measurements, including measurement of maximum urethral closure pressure (MUCP) can form part of the investigation of women prior to SUI surgery and some studies have suggested that women with higher MUCP may have a better surgical outcome. This study aims to determine whether outcome of SUI surgery is related to pre-operative MUCP.
METHODS: All patients undergoing colposuspension or TVT in a large European city between 1998 and 2002 were included. All women underwent pre-operative urodynamics, including measurement of urethral pressure profile; urodynamic data, including MUCP, were determined. Surgical outcome was measured using the ICIQ-FLUTS questionnaire, which was mailed to allow for a minimum follow-up period of 3 years. Surgical outcome was measured by assigning patients to one of three post-operative Stress Urinary Incontinence (SUI) groups. Group 1 (No incontinence), Group 2 (< 1 incontinence episode per day), Group 3 (> 1 incontinence episode per day). Independent statistical analysis was undertaken using STATA® software and a two-way ANOVA (Analysis of Variance) test to determine the relationship between pre-operative MUCP and post-operative SUI group.
RESULTS: A total of 463 postal questionnaires were mailed, with a response rate of 62%, allowing for those who had died or moved away. Of the 285 responders, 218 had undergone colposuspension and 66 had a TVT. Median age, length of follow up and MUCP were 54 years (range 23-81), 77 months (range 47 to 107) and 45 cmH(2) O (range 5 to 105) respectively. Difference in MUCP between the two operation groups (colposuspension and TVT) was not significant (p > 0.19). No significant difference in preoperative MUCP was demonstrated between the three SUI groups, with mean MUCP in the three SUI groups of 50, 45 and 43 cmH(2) 0 respectively, confirming that patients with higher MUCP were not more likely to be in a lower post-operative SUI group (F(2, 237) = 3.42, p < 0.04).
CONCLUSION: Our data demonstrate that women with higher preoperative MUCP do not have a better surgical outcome following stress incontinence surgery.
Copyright © 2011 Wiley Periodicals, Inc.

Entities:  

Mesh:

Year:  2011        PMID: 21780164     DOI: 10.1002/nau.21111

Source DB:  PubMed          Journal:  Neurourol Urodyn        ISSN: 0733-2467            Impact factor:   2.696


  6 in total

Review 1.  Incontinence in the elderly, 'normal' ageing, or unaddressed pathology?

Authors:  William Gibson; Adrian Wagg
Journal:  Nat Rev Urol       Date:  2017-04-11       Impact factor: 14.432

2.  A comparative study of a single-incision sling and a transobturator sling: clinical efficacy and urodynamic changes.

Authors:  Mou-Jong Sun; Ryan Sun; Yi-Ing Li
Journal:  Int Urogynecol J       Date:  2012-09-28       Impact factor: 2.894

3.  Should maximal urethral closure pressure be performed before midurethral sling surgery for stress incontinence? A time to revisit.

Authors:  Monika Vij; Anupreet Dua; Robert M Freeman
Journal:  Int Urogynecol J       Date:  2016-03-24       Impact factor: 2.894

4.  What do we do when a midurethral tape fails? Rediscovery of open colposuspension as a salvage continence operation.

Authors:  Ilias Giarenis; Heleni Mastoroudes; Linda Cardozo; Dudley Robinson
Journal:  Int Urogynecol J       Date:  2012-03-13       Impact factor: 2.894

5.  Analysis of continence reflexes by dynamic urethral pressure recordings in a rat stress urinary incontinence model induced by multiple simulated birth traumas.

Authors:  Joonbeom Kwon; Takahisa Suzuki; Ei-Ichiro Takaoka; Nobutaka Shimizu; Takahiro Shimizu; Shun Takai; Satoru Yoshikawa; William C de Groat; Naoki Yoshimura
Journal:  Am J Physiol Renal Physiol       Date:  2019-07-17

6.  Comparison of midurethral sling outcomes with and without concomitant prolapse repair.

Authors:  E Jung Han; Soo Rim Kim; Sei Kwang Kim; Sang Wook Bai
Journal:  Obstet Gynecol Sci       Date:  2014-01-16
  6 in total

北京卡尤迪生物科技股份有限公司 © 2022-2023.