Literature DB >> 21779594

Similar interactions of natural products with biosynthetic enzymes and therapeutic targets could explain why nature produces such a large proportion of existing drugs.

Esther Kellenberger1, Andreas Hofmann, Ronald J Quinn.   

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Year:  2011        PMID: 21779594     DOI: 10.1039/c1np00026h

Source DB:  PubMed          Journal:  Nat Prod Rep        ISSN: 0265-0568            Impact factor:   13.423


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  17 in total

Review 1.  Opportunities for plant natural products in infection control.

Authors:  Akram M Salam; Cassandra L Quave
Journal:  Curr Opin Microbiol       Date:  2018-09-13       Impact factor: 7.934

Review 2.  The re-emergence of natural products for drug discovery in the genomics era.

Authors:  Alan L Harvey; RuAngelie Edrada-Ebel; Ronald J Quinn
Journal:  Nat Rev Drug Discov       Date:  2015-01-23       Impact factor: 84.694

Review 3.  Is it time for artificial intelligence to predict the function of natural products based on 2D-structure.

Authors:  Miaomiao Liu; Peter Karuso; Yunjiang Feng; Esther Kellenberger; Fei Liu; Can Wang; Ronald J Quinn
Journal:  Medchemcomm       Date:  2019-06-06       Impact factor: 3.597

4.  Combined Scaffold Evaluation and Systems-Level Transcriptome-Based Analysis for Accelerated Lead Optimization Reveals Ribosomal Targeting Spirooxindole Cyclopropanes.

Authors:  Kevin X Rodriguez; Erin N Howe; Emily P Bacher; Miranda Burnette; Jennifer L Meloche; Jayda Meisel; Patricia Schnepp; Xuejuan Tan; Mayland Chang; Jeremiah Zartman; Siyuan Zhang; Brandon L Ashfeld
Journal:  ChemMedChem       Date:  2019-07-01       Impact factor: 3.466

5.  Total synthesis of thiaplakortone a: derivatives as metabolically stable leads for the treatment of malaria.

Authors:  Rebecca H Pouwer; Sophie M Deydier; Phuc Van Le; Brett D Schwartz; Nicole C Franken; Rohan A Davis; Mark J Coster; Susan A Charman; Michael D Edstein; Tina S Skinner-Adams; Katherine T Andrews; Ian D Jenkins; Ronald J Quinn
Journal:  ACS Med Chem Lett       Date:  2013-12-27       Impact factor: 4.345

6.  Advantages of Molecular Weight Identification during Native MS Screening.

Authors:  Ahad Khan; Anne Bresnick; Sean Cahill; Mark Girvin; Steve Almo; Ronald Quinn
Journal:  Planta Med       Date:  2018-05-09       Impact factor: 3.352

7.  Molecular Simplification of Natural Products: Synthesis, Antibacterial Activity, and Molecular Docking Studies of Berberine Open Models.

Authors:  Gualtiero Milani; Maria Maddalena Cavalluzzi; Roberta Solidoro; Lara Salvagno; Laura Quintieri; Angela Di Somma; Antonio Rosato; Filomena Corbo; Carlo Franchini; Angela Duilio; Leonardo Caputo; Solomon Habtemariam; Giovanni Lentini
Journal:  Biomedicines       Date:  2021-04-22

8.  The natural product magnolol as a lead structure for the development of potent cannabinoid receptor agonists.

Authors:  Alexander Fuchs; Viktor Rempel; Christa E Müller
Journal:  PLoS One       Date:  2013-10-30       Impact factor: 3.240

9.  Four new chloro-eremophilane sesquiterpenes from an Antarctic deep-sea derived fungus, Penicillium sp. PR19N-1.

Authors:  Guangwei Wu; Aiqun Lin; Qianqun Gu; Tianjiao Zhu; Dehai Li
Journal:  Mar Drugs       Date:  2013-04-23       Impact factor: 5.118

Review 10.  Physicochemical properties and Mycobacterium tuberculosis transporters: keys to efficacious antitubercular drugs?

Authors:  Elizabeth Fullam; Robert J Young
Journal:  RSC Med Chem       Date:  2020-12-07
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