Literature DB >> 21778066

A clinical trial protocol for second line treatment of malignant brain tumors with BNCT at University of Tsukuba.

H Aiyama1, K Nakai, T Yamamoto, T Nariai, H Kumada, E Ishikawa, T Isobe, K Endo, T Takada, F Yoshida, Y Shibata, A Matsumura.   

Abstract

We have evaluated the efficacy and safety of boron neutron capture therapy (BNCT) for recurrent glioma and malignant brain tumor using a new protocol. One of the two patients enrolled in this trial is a man with recurrent glioblastoma and the other is a woman with anaplastic meningioma. Both are still alive and no severe adverse events have been observed. Our findings suggest that NCT will be safe as a palliative therapy for malignant brain tumors. Copyright Â
© 2011 Elsevier Ltd. All rights reserved.

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Year:  2011        PMID: 21778066     DOI: 10.1016/j.apradiso.2011.04.031

Source DB:  PubMed          Journal:  Appl Radiat Isot        ISSN: 0969-8043            Impact factor:   1.513


  10 in total

1.  Intracavitary moderator balloon combined with (252)Cf brachytherapy and boron neutron capture therapy, improving dosimetry in brain tumour and infiltrations.

Authors:  S F Brandão; T P R Campos
Journal:  Br J Radiol       Date:  2015-04-30       Impact factor: 3.039

2.  Boron neutron capture therapy (BNCT) for liver metastasis in an experimental model: dose–response at five-week follow-up based on retrospective dose assessment in individual rats.

Authors:  Emiliano C C Pozzi; Verónica A Trivillin; Lucas L Colombo; Andrea Monti Hughes; Silvia I Thorp; Jorge E Cardoso; Marcela A Garabalino; Ana J Molinari; Elisa M Heber; Paula Curotto; Marcelo Miller; Maria E Itoiz; Romina F Aromando; David W Nigg; Amanda E Schwint
Journal:  Radiat Environ Biophys       Date:  2013-11       Impact factor: 1.925

3.  Boron neutron capture therapy (BNCT) for liver metastasis: therapeutic efficacy in an experimental model.

Authors:  Emiliano C C Pozzi; Jorge E Cardoso; Lucas L Colombo; Silvia Thorp; Andrea Monti Hughes; Ana J Molinari; Marcela A Garabalino; Elisa M Heber; Marcelo Miller; Maria E Itoiz; Romina F Aromando; David W Nigg; Jorge Quintana; Verónica A Trivillin; Amanda E Schwint
Journal:  Radiat Environ Biophys       Date:  2012-04-28       Impact factor: 1.925

4.  In vitro studies of DNA damage and repair mechanisms induced by BNCT in a poorly differentiated thyroid carcinoma cell line.

Authors:  C Rodriguez; M Carpano; P Curotto; S Thorp; M Casal; G Juvenal; M Pisarev; M A Dagrosa
Journal:  Radiat Environ Biophys       Date:  2018-02-16       Impact factor: 1.925

5.  Radiobiological response of U251MG, CHO-K1 and V79 cell lines to accelerator-based boron neutron capture therapy.

Authors:  Eisuke Sato; Alexander Zaboronok; Tetsuya Yamamoto; Kei Nakai; Sergey Taskaev; Olga Volkova; Ludmila Mechetina; Alexander Taranin; Vladimir Kanygin; Tomonori Isobe; Bryan J Mathis; Akira Matsumura
Journal:  J Radiat Res       Date:  2018-03-01       Impact factor: 2.724

Review 6.  Boron Neutron Capture Therapy and Photodynamic Therapy for High-Grade Meningiomas.

Authors:  Yukiko Nakahara; Hiroshi Ito; Jun Masuoka; Tatsuya Abe
Journal:  Cancers (Basel)       Date:  2020-05-23       Impact factor: 6.639

Review 7.  Boron Neutron Capture Therapy: A Review of Clinical Applications.

Authors:  Timothy D Malouff; Danushka S Seneviratne; Daniel K Ebner; William C Stross; Mark R Waddle; Daniel M Trifiletti; Sunil Krishnan
Journal:  Front Oncol       Date:  2021-02-26       Impact factor: 6.244

Review 8.  The use of radiosensitizing agents in the therapy of glioblastoma multiforme-a comprehensive review.

Authors:  Niklas Benedikt Pepper; Walter Stummer; Hans Theodor Eich
Journal:  Strahlenther Onkol       Date:  2022-05-03       Impact factor: 4.033

Review 9.  Current status of boron neutron capture therapy of high grade gliomas and recurrent head and neck cancer.

Authors:  Rolf F Barth; M Graca H Vicente; Otto K Harling; W S Kiger; Kent J Riley; Peter J Binns; Franz M Wagner; Minoru Suzuki; Teruhito Aihara; Itsuro Kato; Shinji Kawabata
Journal:  Radiat Oncol       Date:  2012-08-29       Impact factor: 3.481

10.  Aza-BODIPY: A New Vector for Enhanced Theranostic Boron Neutron Capture Therapy Applications.

Authors:  Ghadir Kalot; Amélie Godard; Benoît Busser; Jacques Pliquett; Mans Broekgaarden; Vincent Motto-Ros; Karl David Wegner; Ute Resch-Genger; Ulli Köster; Franck Denat; Jean-Luc Coll; Ewen Bodio; Christine Goze; Lucie Sancey
Journal:  Cells       Date:  2020-08-25       Impact factor: 6.600

  10 in total

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