| Literature DB >> 21778062 |
Luba Dubinsky1, Bastiaan P Krom, Michael M Meijler.
Abstract
Diazirines are among the smallest photoreactive groups that form a reactive carbene upon light irradiation. This feature has been widely utilized in photoaffinity labeling to study ligand-receptor, ligand-enzyme and protein-protein interactions, and in the isolation and identification of unknown proteins. This review summarizes recent advances in the use of diazirines in photoaffinity labeling.Entities:
Mesh:
Substances:
Year: 2011 PMID: 21778062 DOI: 10.1016/j.bmc.2011.06.066
Source DB: PubMed Journal: Bioorg Med Chem ISSN: 0968-0896 Impact factor: 3.641