BACKGROUND: Aspiration pneumonia is associated with a high morbidity and mortality in elderly patients. In order to provide risk-adapted medical care, it is necessary to establish valid prognostic tools for these patients. OBJECTIVE: The value of two well-established scores to assess prognosis in community-acquired pneumonia (CAP), i.e., CURB-65 and the Pneumonia Severity Index (PSI), was evaluated in elderly patients hospitalized for aspiration pneumonia. MATERIAL AND METHODS: A total of 209 patients hospitalized with aspiration pneumonia between 2001 and 2005 in a single center were evaluated using PSI and CURB-65. For comparison of morbidity and mortality, an equally large group of inpatients with CAP was analyzed. RESULTS: The mean age of patients with aspiration pneumonia was 76.7 ± 13.4 years, and 104 (49.8 %) were female. Patients with aspiration pneumonia more frequently showed a history of cancer, hypotension, and hyponatriemia on admission. Mortality was clearly higher in comparison to patients with CAP (39.2% vs. 16.3%). The Odds Ratio (OR) for mortality was 1.03 (95% CI 0.59; 1.79) for a CURB-65 score of 3-5 points compared to 0-2 points. In cases of CAP, OR showed a statistically significant increase of risk (OR 2.50; 95% CI 1.04; 6.06), for CURB-65 scores of 3-5 points vs. 0-2 points). In aspiration pneumonia, the PSI showed a trend towards increasing mortality within higher risk class. CONCLUSIONS: In geriatric patients hospitalized with aspiration pneumonia, CURB-65 and PSI have no prognostic value.
BACKGROUND:Aspiration pneumonia is associated with a high morbidity and mortality in elderly patients. In order to provide risk-adapted medical care, it is necessary to establish valid prognostic tools for these patients. OBJECTIVE: The value of two well-established scores to assess prognosis in community-acquired pneumonia (CAP), i.e., CURB-65 and the Pneumonia Severity Index (PSI), was evaluated in elderly patients hospitalized for aspiration pneumonia. MATERIAL AND METHODS: A total of 209 patients hospitalized with aspiration pneumonia between 2001 and 2005 in a single center were evaluated using PSI and CURB-65. For comparison of morbidity and mortality, an equally large group of inpatients with CAP was analyzed. RESULTS: The mean age of patients with aspiration pneumonia was 76.7 ± 13.4 years, and 104 (49.8 %) were female. Patients with aspiration pneumonia more frequently showed a history of cancer, hypotension, and hyponatriemia on admission. Mortality was clearly higher in comparison to patients with CAP (39.2% vs. 16.3%). The Odds Ratio (OR) for mortality was 1.03 (95% CI 0.59; 1.79) for a CURB-65 score of 3-5 points compared to 0-2 points. In cases of CAP, OR showed a statistically significant increase of risk (OR 2.50; 95% CI 1.04; 6.06), for CURB-65 scores of 3-5 points vs. 0-2 points). In aspiration pneumonia, the PSI showed a trend towards increasing mortality within higher risk class. CONCLUSIONS: In geriatric patients hospitalized with aspiration pneumonia, CURB-65 and PSI have no prognostic value.
Authors: Ali A El-Solh; Celestino Pietrantoni; Abid Bhat; Alan T Aquilina; Mifue Okada; Vikas Grover; Nancy Gifford Journal: Am J Respir Crit Care Med Date: 2003-04-10 Impact factor: 21.405
Authors: O Leroy; C Vandenbussche; C Coffinier; C Bosquet; H Georges; B Guery; D Thevenin; G Beaucaire Journal: Am J Respir Crit Care Med Date: 1997-12 Impact factor: 21.405
Authors: JoAnne Robbins; Gary Gensler; Jacqueline Hind; Jeri A Logemann; Anne S Lindblad; Diane Brandt; Herbert Baum; David Lilienfeld; Steven Kosek; Donna Lundy; Karen Dikeman; Marta Kazandjian; Gary D Gramigna; Susan McGarvey-Toler; Patricia J Miller Gardner Journal: Ann Intern Med Date: 2008-04-01 Impact factor: 25.391
Authors: Ulrich Thiem; David Niklaus; Bettina Sehlhoff; Christoph Stückle; Hans Jürgen Heppner; Heinz Gerd Endres; Ludger Pientka Journal: Age Ageing Date: 2009-09-03 Impact factor: 10.668
Authors: Michael J Lanspa; Paula Peyrani; Timothy Wiemken; Emily L Wilson; Julio A Ramirez; Nathan C Dean Journal: J Hosp Med Date: 2014-11-01 Impact factor: 2.960
Authors: Dheeraj Gupta; Ritesh Agarwal; Ashutosh Nath Aggarwal; Navneet Singh; Narayan Mishra; G C Khilnani; J K Samaria; S N Gaur; S K Jindal Journal: Lung India Date: 2012-07