Literature DB >> 24360244

The management of community-acquired pneumonia in the elderly.

Paola Faverio1, Stefano Aliberti2, Giuseppe Bellelli3, Giulia Suigo4, Sara Lonni4, Alberto Pesci4, Marcos I Restrepo5.   

Abstract

Pneumonia is one of the main causes of morbidity and mortality in the elderly. The elderly population has exponentially increased in the last decades and the current epidemiological trends indicate that it is expected to further increase. Therefore, recognizing the special needs of older people is of paramount importance. In this review we address the main differences between elderly and adult patients with pneumonia. We focus on several aspects, including the atypical clinical presentation of pneumonia in the elderly, the methods to assess severity of illness, the appropriate setting of care, and the management of comorbidities. We also discuss how to approach the common complications of severe pneumonia, including acute respiratory failure and severe sepsis. Moreover, we debate whether or not elderly patients are at higher risk of infection due to multi-drug resistant pathogens and which risk factors should be considered when choosing the antibiotic therapy. We highlight the differences in the definition of clinical stability and treatment failure between adults and elderly patients. Finally, we review the main outcomes, preventive and supportive measures to be considered in elderly patients with pneumonia.
Copyright © 2013 European Federation of Internal Medicine. All rights reserved.

Entities:  

Keywords:  Acute respiratory failure; Antibiotic treatment; Community-acquired pneumonia; Elderly; Functional status; Severity

Mesh:

Substances:

Year:  2013        PMID: 24360244      PMCID: PMC4102338          DOI: 10.1016/j.ejim.2013.12.001

Source DB:  PubMed          Journal:  Eur J Intern Med        ISSN: 0953-6205            Impact factor:   4.487


  95 in total

1.  The association of plasma IL-6 levels with functional disability in community-dwelling elderly.

Authors:  H J Cohen; C F Pieper; T Harris; K M Rao; M S Currie
Journal:  J Gerontol A Biol Sci Med Sci       Date:  1997-07       Impact factor: 6.053

2.  Prior pneumococcal vaccination is associated with reduced death, complications, and length of stay among hospitalized adults with community-acquired pneumonia.

Authors:  David N Fisman; Elias Abrutyn; Kimberly A Spaude; Alex Kim; Cheryl Kirchner; Jennifer Daley
Journal:  Clin Infect Dis       Date:  2006-03-13       Impact factor: 9.079

3.  Cardiac complications in patients with community-acquired pneumonia: incidence, timing, risk factors, and association with short-term mortality.

Authors:  Vicente F Corrales-Medina; Daniel M Musher; George A Wells; Julio A Chirinos; Li Chen; Michael J Fine
Journal:  Circulation       Date:  2012-01-04       Impact factor: 29.690

4.  Non-invasive ventilation in elderly patients with acute hypercapnic respiratory failure: a randomised controlled trial.

Authors:  Stefano Nava; Mario Grassi; Francesco Fanfulla; Guido Domenighetti; Annalisa Carlucci; Andreas Perren; Daniela Dell'Orso; Michele Vitacca; Piero Ceriana; Zuhal Karakurt; Enrico Clini
Journal:  Age Ageing       Date:  2011-02-22       Impact factor: 10.668

5.  Frailty in older adults: evidence for a phenotype.

Authors:  L P Fried; C M Tangen; J Walston; A B Newman; C Hirsch; J Gottdiener; T Seeman; R Tracy; W J Kop; G Burke; M A McBurnie
Journal:  J Gerontol A Biol Sci Med Sci       Date:  2001-03       Impact factor: 6.053

6.  Impact of obesity on outcomes for patients hospitalised with pneumonia.

Authors:  Phoebe King; Eric M Mortensen; Mary Bollinger; Marcos I Restrepo; Laurel A Copeland; Mary Jo V Pugh; Brandy Nakashima; Antonio Anzueto; Polly Hitchcock Noël
Journal:  Eur Respir J       Date:  2012-08-30       Impact factor: 16.671

7.  Early mobilization of patients hospitalized with community-acquired pneumonia.

Authors:  Linda M Mundy; Terry L Leet; Kate Darst; Mark A Schnitzler; William Claiborne Dunagan
Journal:  Chest       Date:  2003-09       Impact factor: 9.410

8.  The MDS-CHESS scale: a new measure to predict mortality in institutionalized older people.

Authors:  John P Hirdes; Dinnus H Frijters; Gary F Teare
Journal:  J Am Geriatr Soc       Date:  2003-01       Impact factor: 5.562

9.  Prevalence and outcomes of low mobility in hospitalized older patients.

Authors:  Cynthia J Brown; Rebecca J Friedkin; Sharon K Inouye
Journal:  J Am Geriatr Soc       Date:  2004-08       Impact factor: 5.562

10.  The burden of community-acquired pneumonia in seniors: results of a population-based study.

Authors:  Michael L Jackson; Kathleen M Neuzil; William W Thompson; David K Shay; Onchee Yu; Christi A Hanson; Lisa A Jackson
Journal:  Clin Infect Dis       Date:  2004-11-08       Impact factor: 9.079

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  28 in total

Review 1.  Challenges with Diagnosing and Managing Sepsis in Older Adults.

Authors:  Kalin M Clifford; Eliza A Dy-Boarman; Krystal K Haase; Kristen Maxvill; Steven E Pass; Carlos A Alvarez
Journal:  Expert Rev Anti Infect Ther       Date:  2016-01-14       Impact factor: 5.091

Review 2.  Meta-review: adverse effects of inhaled corticosteroids relevant to older patients.

Authors:  Katharina Mattishent; Menaka Thavarajah; Patricia Blanco; Daniel Gilbert; Andrew M Wilson; Yoon K Loke
Journal:  Drugs       Date:  2014-04       Impact factor: 9.546

Review 3.  Managing community acquired pneumonia in the elderly - the next generation of pharmacotherapy on the horizon.

Authors:  B Amalakuhan; K L Echevarria; M I Restrepo
Journal:  Expert Opin Pharmacother       Date:  2017-06-21       Impact factor: 3.889

4.  Age-Related Differences in Clinical Characteristics and Esophageal Motility in Patients with Dysphagia.

Authors:  Rui Nakato; Noriaki Manabe; Tomoari Kamada; Hideo Matsumoto; Akiko Shiotani; Jiro Hata; Ken Haruma
Journal:  Dysphagia       Date:  2016-12-02       Impact factor: 3.438

Review 5.  Biomarkers, diagnosis and management of sepsis-induced acute kidney injury: a narrative review.

Authors:  Zhongheng Zhang
Journal:  Heart Lung Vessel       Date:  2015

6.  Lung ultrasound and chest x-ray for detecting pneumonia in an acute geriatric ward.

Authors:  Andrea Ticinesi; Fulvio Lauretani; Antonio Nouvenne; Giulia Mori; Giulia Chiussi; Marcello Maggio; Tiziana Meschi
Journal:  Medicine (Baltimore)       Date:  2016-07       Impact factor: 1.889

7.  Lower Body Mass Index is a Risk Factor for In-Hospital Mortality of Elderly Japanese Patients Treated with Ampicillin/sulbactam.

Authors:  Makoto Miura; Akiko Kuwahara; Akinori Tomozawa; Naoki Omae; Motohiro Yamamori; Kaori Kadoyama; Toshiyuki Sakaeda
Journal:  Int J Med Sci       Date:  2016-09-19       Impact factor: 3.738

8.  A Non-Human Primate Model of Severe Pneumococcal Pneumonia.

Authors:  Luis F Reyes; Marcos I Restrepo; Cecilia A Hinojosa; Nilam J Soni; Anukul T Shenoy; Ryan P Gilley; Norberto Gonzalez-Juarbe; Julio R Noda; Vicki T Winter; Melissa A de la Garza; Robert E Shade; Jacqueline J Coalson; Luis D Giavedoni; Antonio Anzueto; Carlos J Orihuela
Journal:  PLoS One       Date:  2016-11-17       Impact factor: 3.240

9.  Age-related differences in management and outcomes in hospitalized healthy and well-functioning bacteremic pneumococcal pneumonia patients: a cohort study.

Authors:  Luis A Ruiz; Pedro P España; Ainhoa Gómez; Amaia Bilbao; Carmen Jaca; Amaia Arámburu; Alberto Capelastegui; Marcos I Restrepo; Rafael Zalacain
Journal:  BMC Geriatr       Date:  2017-06-20       Impact factor: 3.921

10.  The association of serum procalcitonin and high-sensitivity C-reactive protein with pneumonia in elderly multimorbid patients with respiratory symptoms: retrospective cohort study.

Authors:  Antonio Nouvenne; Andrea Ticinesi; Giuseppina Folesani; Nicoletta Cerundolo; Beatrice Prati; Ilaria Morelli; Loredana Guida; Fulvio Lauretani; Marcello Maggio; Rosalia Aloe; Giuseppe Lippi; Tiziana Meschi
Journal:  BMC Geriatr       Date:  2016-01-15       Impact factor: 3.921

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