Literature DB >> 21767474

Functional role for transporter isoforms in optimizing membrane transport.

Alexander M Berezhkovskii, Vladimir A Lizunov, Joshua Zimmerberg, Sergey M Bezrukov.   

Abstract

Quantitative analysis of carrier parameters demonstrates that with decreasing substrate concentration the optimal strength of substrate-carrier interaction which maximizes the flux across the membrane increases and requires less fine-tuning than at higher concentrations of the substrate.
Copyright © 2011 Biophysical Society. Published by Elsevier Inc. All rights reserved.

Mesh:

Substances:

Year:  2011        PMID: 21767474      PMCID: PMC3136783          DOI: 10.1016/j.bpj.2011.06.004

Source DB:  PubMed          Journal:  Biophys J        ISSN: 0006-3495            Impact factor:   4.033


  9 in total

1.  On translocation through a membrane channel via an internal binding site: kinetics and voltage dependence.

Authors:  Gerhard Schwarz; Christophe Danelon; Mathias Winterhalter
Journal:  Biophys J       Date:  2003-05       Impact factor: 4.033

2.  Optimizing transport of metabolites through large channels: molecular sieves with and without binding.

Authors:  Alexander M Berezhkovskii; Sergey M Bezrukov
Journal:  Biophys J       Date:  2004-12-30       Impact factor: 4.033

3.  Molecular transport through channels and pores: effects of in-channel interactions and blocking.

Authors:  Wolfgang R Bauer; Walter Nadler
Journal:  Proc Natl Acad Sci U S A       Date:  2006-07-21       Impact factor: 11.205

4.  Channel-facilitated molecular transport across membranes: attraction, repulsion, and asymmetry.

Authors:  Anatoly B Kolomeisky
Journal:  Phys Rev Lett       Date:  2007-01-26       Impact factor: 9.161

5.  Effects of multiple occupancy and interparticle interactions on selective transport through narrow channels: theory versus experiment.

Authors:  Anton Zilman
Journal:  Biophys J       Date:  2009-02-18       Impact factor: 4.033

Review 6.  Transporter explosion: update on uptake.

Authors:  G R Uhl; P R Hartig
Journal:  Trends Pharmacol Sci       Date:  1992-12       Impact factor: 14.819

Review 7.  Monocarboxylate transport in erythrocytes.

Authors:  B Deuticke
Journal:  J Membr Biol       Date:  1982       Impact factor: 1.843

Review 8.  Glucose transporters in the 21st Century.

Authors:  Bernard Thorens; Mike Mueckler
Journal:  Am J Physiol Endocrinol Metab       Date:  2009-12-15       Impact factor: 4.310

Review 9.  The ABCs of solute carriers: physiological, pathological and therapeutic implications of human membrane transport proteinsIntroduction.

Authors:  Matthias A Hediger; Michael F Romero; Ji-Bin Peng; Andreas Rolfs; Hitomi Takanaga; Elspeth A Bruford
Journal:  Pflugers Arch       Date:  2003-11-18       Impact factor: 3.657

  9 in total
  1 in total

1.  Dependence of the Enzymatic Velocity on the Substrate Dissociation Rate.

Authors:  Alexander M Berezhkovskii; Attila Szabo; T Rotbart; M Urbakh; Anatoly B Kolomeisky
Journal:  J Phys Chem B       Date:  2016-12-01       Impact factor: 2.991

  1 in total

北京卡尤迪生物科技股份有限公司 © 2022-2023.