Literature DB >> 21765095

IRiS: construction of ARG networks at genomic scales.

Asif Javed1, Marc Pybus, Marta Melé, Filippo Utro, Jaume Bertranpetit, Francesc Calafell, Laxmi Parida.   

Abstract

SUMMARY: Given a set of extant haplotypes IRiS first detects high confidence recombination events in their shared genealogy. Next using the local sequence topology defined by each detected event, it integrates these recombinations into an ancestral recombination graph. While the current system has been calibrated for human population data, it is easily extendible to other species as well. AVAILABILITY: IRiS (Identification of Recombinations in Sequences) binary files are available for non-commercial use in both Linux and Microsoft Windows, 32 and 64 bit environments from https://researcher.ibm.com/researcher/view_project.php?id = 2303 CONTACT: parida@us.ibm.com.

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Mesh:

Year:  2011        PMID: 21765095     DOI: 10.1093/bioinformatics/btr423

Source DB:  PubMed          Journal:  Bioinformatics        ISSN: 1367-4803            Impact factor:   6.937


  5 in total

1.  Recombination networks as genetic markers in a human variation study of the Old World.

Authors:  Asif Javed; Marta Melé; Marc Pybus; Pierre Zalloua; Marc Haber; David Comas; Mihai G Netea; Oleg Balanovsky; Elena Balanovska; Li Jin; Yajun Yang; Ganeshprasad Arunkumar; Ramasamy Pitchappan; Jaume Bertranpetit; Francesc Calafell; Laxmi Parida
Journal:  Hum Genet       Date:  2011-10-18       Impact factor: 4.132

2.  ARG-based genome-wide analysis of cacao cultivars.

Authors:  Filippo Utro; Omar Eduardo Cornejo; Donald Livingstone; Juan Carlos Motamayor; Laxmi Parida
Journal:  BMC Bioinformatics       Date:  2012-12-19       Impact factor: 3.169

3.  The importance and application of the ancestral recombination graph.

Authors:  Miguel Arenas
Journal:  Front Genet       Date:  2013-10-14       Impact factor: 4.599

4.  Sum of parts is greater than the whole: inference of common genetic history of populations.

Authors:  Filippo Utro; Marc Pybus; Laxmi Parida
Journal:  BMC Genomics       Date:  2013-01-21       Impact factor: 3.969

5.  ARG-walker: inference of individual specific strengths of meiotic recombination hotspots by population genomics analysis.

Authors:  Hao Chen; Peng Yang; Jing Guo; Chee Keong Kwoh; Teresa M Przytycka; Jie Zheng
Journal:  BMC Genomics       Date:  2015-12-09       Impact factor: 3.969

  5 in total

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