Literature DB >> 21764920

The endolysin-binding domain encompasses the N-terminal region of the mycobacteriophage Ms6 Gp1 chaperone.

Maria João Catalão1, Filipa Gil, José Moniz-Pereira, Madalena Pimentel.   

Abstract

The intermolecular interactions of the mycobacteriophage Ms6 secretion chaperone with endolysin were characterized. The 384-amino-acid lysin (lysin(384))-binding domain was found to encompass the N-terminal region of Gp1, which is also essential for a lysis phenotype in Escherichia coli. In addition, a GXXXG-like motif involved in Gp1 homo-oligomerization was identified within the C-terminal region.
Copyright © 2011, American Society for Microbiology. All Rights Reserved.

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Year:  2011        PMID: 21764920      PMCID: PMC3165679          DOI: 10.1128/JB.00380-11

Source DB:  PubMed          Journal:  J Bacteriol        ISSN: 0021-9193            Impact factor:   3.490


  18 in total

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