PURPOSE: We demonstrate clinical features, therapy and outcome of 14 patients with symptomatic spinal cavernous malformations (CM). METHODS: We retrospectively reviewed all patients who underwent microsurgical treatment of symptomatic spinal CM during the last decade in our department through an analysis of our database. RESULTS: We analyzed the data of 14 patients (11 females, 3 males) with symptomatic spinal CM in a range of 16-77 years (mean age 47.8 years). Seven patients (50%) experienced significant improvement of their symptoms rapidly after surgery. The remaining seven patients presented new non pre-existing complaints, which improved gradually with a favourable outcome at the last follow-up examination in six cases. CONCLUSION: Microsurgical treatment under perioperative electrophysiological monitoring is justified to prevent severe neurofunctional deterioration in symptomatic spinal CM. Although some of the patients deteriorate after surgery, the symptoms are rapidly declining with a favourable outcome in majority of them.
PURPOSE: We demonstrate clinical features, therapy and outcome of 14 patients with symptomatic spinal cavernous malformations (CM). METHODS: We retrospectively reviewed all patients who underwent microsurgical treatment of symptomatic spinal CM during the last decade in our department through an analysis of our database. RESULTS: We analyzed the data of 14 patients (11 females, 3 males) with symptomatic spinal CM in a range of 16-77 years (mean age 47.8 years). Seven patients (50%) experienced significant improvement of their symptoms rapidly after surgery. The remaining seven patients presented new non pre-existing complaints, which improved gradually with a favourable outcome at the last follow-up examination in six cases. CONCLUSION: Microsurgical treatment under perioperative electrophysiological monitoring is justified to prevent severe neurofunctional deterioration in symptomatic spinal CM. Although some of the patients deteriorate after surgery, the symptoms are rapidly declining with a favourable outcome in majority of them.
Authors: D Rigamonti; M N Hadley; B P Drayer; P C Johnson; K Hoenig-Rigamonti; J T Knight; R F Spetzler Journal: N Engl J Med Date: 1988-08-11 Impact factor: 91.245
Authors: Louis J Kim; Jeffrey D Klopfenstein; Joseph M Zabramski; Volker K H Sonntag; Robert F Spetzler Journal: Neurosurgery Date: 2006-01 Impact factor: 4.654
Authors: H D Craig; M Günel; O Cepeda; E W Johnson; L Ptacek; G K Steinberg; C S Ogilvy; M J Berg; S C Crawford; R M Scott; E Steichen-Gersdorf; R Sabroe; C T Kennedy; G Mettler; M J Beis; A Fryer; I A Awad; R P Lifton Journal: Hum Mol Genet Date: 1998-11 Impact factor: 6.150