Literature DB >> 21752948

Subcutaneous immunization with baculovirus surface-displayed hemagglutinin of pandemic H1N1 Influenza A virus induces protective immunity in mice.

Mookkan Prabakaran1, Tao Meng, Fang He, Tan Yunrui, Jia Qiang, Raymond Tzer Pin Lin, Jimmy Kwang.   

Abstract

The protective immunity of baculovirus displaying influenza virus hemagglutinin (BacHA) against influenza 2009 H1N1 virus infection in a murine model was investigated. The results showed that mice vaccinated with live BacHA or an inactive form of adjuvanted BacHA had enhanced specific antibody responses and induced protective immunity against 2009 H1N1 virus infection, suggesting the potential of baculovirus as a live or inactivated vaccine.

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Year:  2011        PMID： 21752948      PMCID： PMC3165240          DOI： 10.1128/CVI.05114-11

Source DB:  PubMed          Journal:  Clin Vaccine Immunol        ISSN： 1556-679X


  14 in total

Review 1.  Broadening the approaches to developing more effective vaccines.

Authors:  L A Babiuk
Journal:  Vaccine       Date:  1999-03-26       Impact factor: 3.641

2.  Safety and immunogenicity of a recombinant hemagglutinin vaccine for H5 influenza in humans.

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Review 3.  Recombinant proteins produced in insect cells.

Authors:  John Treanor
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Review 4.  Baculovirus as vaccine vectors.

Authors:  Selvaraj Madhan; Mookkan Prabakaran; Jimmy Kwang
Journal:  Curr Gene Ther       Date:  2010-06       Impact factor: 4.391

5.  Effect of different baculovirus inactivation procedures on the integrity and immunogenicity of porcine parvovirus-like particles.

Authors:  P Rueda; J Fominaya; J P Langeveld; C Bruschke; C Vela; J I Casal
Journal:  Vaccine       Date:  2000-11-22       Impact factor: 3.641

6.  Involvement of the Toll-like receptor 9 signaling pathway in the induction of innate immunity by baculovirus.

Authors:  Takayuki Abe; Hiroaki Hemmi; Hironobu Miyamoto; Kohji Moriishi; Shinichi Tamura; Hiroshi Takaku; Shizuo Akira; Yoshiharu Matsuura
Journal:  J Virol       Date:  2005-03       Impact factor: 5.103

7.  Efficacy of nucleoprotein and haemagglutinin antigens expressed in fowlpox virus as vaccine for influenza in chickens.

Authors:  R G Webster; Y Kawaoka; J Taylor; R Weinberg; E Paoletti
Journal:  Vaccine       Date:  1991-05       Impact factor: 3.641

8.  Safety and immunogenicity of a baculovirus-expressed hemagglutinin influenza vaccine: a randomized controlled trial.

Authors:  John J Treanor; Gilbert M Schiff; Frederick G Hayden; Rebecca C Brady; C Mhorag Hay; Anthony L Meyer; Jeanne Holden-Wiltse; Hua Liang; Adam Gilbert; Manon Cox
Journal:  JAMA       Date:  2007-04-11       Impact factor: 56.272

9.  Evaluation of different methods of inactivation of Newcastle disease virus and avian influenza virus in egg fluids and serum.

Authors:  D J King
Journal:  Avian Dis       Date:  1991 Jul-Sep       Impact factor: 1.577

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Authors:  Amorsolo L Suguitan; Josephine McAuliffe; Kimberly L Mills; Hong Jin; Greg Duke; Bin Lu; Catherine J Luke; Brian Murphy; David E Swayne; George Kemble; Kanta Subbarao
Journal:  PLoS Med       Date:  2006-09       Impact factor: 11.069
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  3 in total

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Journal:  Viruses       Date:  2018-05-31       Impact factor: 5.048

2.  Intranasal immunization of baculovirus displayed hemagglutinin confers complete protection against mouse adapted highly pathogenic H7N7 reassortant influenza virus.

Authors:  Subaschandrabose Rajesh Kumar; Syed Musthaq Syed Khader; Tanja K Kiener; Milene Szyporta; Jimmy Kwang
Journal:  PLoS One       Date:  2013-06-07       Impact factor: 3.240

Review 3.  Recent Progress towards Novel EV71 Anti-Therapeutics and Vaccines.

Authors:  Qingyong Ng; Fang He; Jimmy Kwang
Journal:  Viruses       Date:  2015-12-08       Impact factor: 5.048
  3 in total

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