PURPOSE: Interruption of oral antiplatelet agents for noncardiac surgery places patients who have received coronary stent implantation at high risk of coronary events, including stent thrombosis. We investigated retrospectively perioperative management for patients with coronary stents undergoing thoracic surgery. METHODS: We investigated 38 patients (age, 38-83 years; 33 men and 5 women) who underwent thoracic surgery (35 lung cancer resections and 3 other procedures) after coronary stent implantation at our hospital between January 2006 and August 2010. Data on implanted stents, perioperative medications, and cardiac and hemorrhagic complications were analyzed. RESULTS: Sirolimus-eluting stents (n = 18) and bare-metal stents (n = 20) were implanted. Regarding oral antiplatelet agents, 21 patients received aspirin, 16 received thienopyridine derivative and aspirin, and 1 received no oral antiplatelet agents. Oral antiplatelet agents were stopped 3-7 days before surgery. Perioperative heparinization was performed in 16 patients. Oral antiplatelet agents were restarted after confirmation of hemostasis and the lack of need for further invasive procedures (median, 4 days after surgery). No major cardiac events including stent thrombosis developed. There were no excessive intraoperative bleeding events related to oral antiplatelet agents or heparin. CONCLUSIONS: In our patients, no coronary events occurred with the short-term stopping of oral antiplatelet agents for thoracic surgery.
PURPOSE: Interruption of oral antiplatelet agents for noncardiac surgery places patients who have received coronary stent implantation at high risk of coronary events, including stent thrombosis. We investigated retrospectively perioperative management for patients with coronary stents undergoing thoracic surgery. METHODS: We investigated 38 patients (age, 38-83 years; 33 men and 5 women) who underwent thoracic surgery (35 lung cancer resections and 3 other procedures) after coronary stent implantation at our hospital between January 2006 and August 2010. Data on implanted stents, perioperative medications, and cardiac and hemorrhagic complications were analyzed. RESULTS:Sirolimus-eluting stents (n = 18) and bare-metal stents (n = 20) were implanted. Regarding oral antiplatelet agents, 21 patients received aspirin, 16 received thienopyridine derivative and aspirin, and 1 received no oral antiplatelet agents. Oral antiplatelet agents were stopped 3-7 days before surgery. Perioperative heparinization was performed in 16 patients. Oral antiplatelet agents were restarted after confirmation of hemostasis and the lack of need for further invasive procedures (median, 4 days after surgery). No major cardiac events including stent thrombosis developed. There were no excessive intraoperative bleeding events related to oral antiplatelet agents or heparin. CONCLUSIONS: In our patients, no coronary events occurred with the short-term stopping of oral antiplatelet agents for thoracic surgery.
Authors: Arvind K Sharma; Andrew E Ajani; Shadi M Hamwi; Parimal Maniar; Shilen V Lakhani; Ron Waksman; Joseph Lindsay Journal: Catheter Cardiovasc Interv Date: 2004-10 Impact factor: 2.692
Authors: Lee A Fleisher; Joshua A Beckman; Kenneth A Brown; Hugh Calkins; Elliot L Chaikof; Kirsten E Fleischmann; William K Freeman; James B Froehlich; Edward K Kasper; Judy R Kersten; Barbara Riegel; John F Robb Journal: Circulation Date: 2009-11-02 Impact factor: 29.690
Authors: P Alexander Compton; Ahmad A Zankar; Adebola O Adesanya; Subhash Banerjee; Emmanouil S Brilakis Journal: Am J Cardiol Date: 2006-09-07 Impact factor: 2.778
Authors: M B Leon; D S Baim; J J Popma; P C Gordon; D E Cutlip; K K Ho; A Giambartolomei; D J Diver; D M Lasorda; D O Williams; S J Pocock; R E Kuntz Journal: N Engl J Med Date: 1998-12-03 Impact factor: 91.245
Authors: Christopher P Childers; Melinda Maggard-Gibbons; Jesus G Ulloa; Ian T MacQueen; Isomi M Miake-Lye; Roberta Shanman; Selene Mak; Jessica M Beroes; Paul G Shekelle Journal: Syst Rev Date: 2018-01-10