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Literature DB >> 21750086

FIP1L1/RARA with breakpoint at FIP1L1 intron 13: a variant translocation in acute promyelocytic leukemia.

Juliane Menezes, Francesco Acquadro, Concepción Perez-Pons de la Villa, Félix García-Sánchez, Sara Álvarez, Juan C Cigudosa.

Abstract

Entities: Disease Gene

Mesh：

Substances：

Year: 2011 PMID： 21750086 PMCID： PMC3186322 DOI： 10.3324/haematol.2011.047134

Source DB: PubMed Journal: Haematologica ISSN： 0390-6078 Impact factor: 9.941

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12 in total

1. Activation of FIP1L1-PDGFRalpha requires disruption of the juxtamembrane domain of PDGFRalpha and is FIP1L1-independent.

Authors: Elizabeth H Stover; Jing Chen; Cedric Folens; Benjamin H Lee; Nicole Mentens; Peter Marynen; Ifor R Williams; D Gary Gilliland; Jan Cools
Journal: Proc Natl Acad Sci U S A Date: 2006-05-11 Impact factor: 11.205

2. Fusion of FIP1L1 and RARA as a result of a novel t(4;17)(q12;q21) in a case of juvenile myelomonocytic leukemia.

Authors: A Buijs; M Bruin
Journal: Leukemia Date: 2007-02-15 Impact factor: 11.528

3. The seventh pathogenic fusion gene FIP1L1-RARA was isolated from a t(4;17)-positive acute promyelocytic leukemia.

Authors: Takeshi Kondo; Akio Mori; Stephanie Darmanin; Satoshi Hashino; Junji Tanaka; Masahiro Asaka
Journal: Haematologica Date: 2008-07-04 Impact factor: 9.941

Review 4. Acute promyelocytic leukaemia: novel insights into the mechanisms of cure.

Authors: Hugues de Thé; Zhu Chen
Journal: Nat Rev Cancer Date: 2010-10-22 Impact factor: 60.716

5. A tyrosine kinase created by fusion of the PDGFRA and FIP1L1 genes as a therapeutic target of imatinib in idiopathic hypereosinophilic syndrome.

Authors: Jan Cools; Daniel J DeAngelo; Jason Gotlib; Elizabeth H Stover; Robert D Legare; Jorges Cortes; Jeffrey Kutok; Jennifer Clark; Ilene Galinsky; James D Griffin; Nicholas C P Cross; Ayalew Tefferi; James Malone; Rafeul Alam; Stanley L Schrier; Janet Schmid; Michal Rose; Peter Vandenberghe; Gregor Verhoef; Marc Boogaerts; Iwona Wlodarska; Hagop Kantarjian; Peter Marynen; Steven E Coutre; Richard Stone; D Gary Gilliland
Journal: N Engl J Med Date: 2003-03-27 Impact factor: 91.245

Review 6. Translocations of the RARalpha gene in acute promyelocytic leukemia.

Authors: A Zelent; F Guidez; A Melnick; S Waxman; J D Licht
Journal: Oncogene Date: 2001-10-29 Impact factor: 9.867

7. The PRKAR1A gene is fused to RARA in a new variant acute promyelocytic leukemia.

Authors: Alberto Catalano; Mark A Dawson; Karthiga Somana; Stephen Opat; Anthony Schwarer; Lynda J Campbell; Harry Iland
Journal: Blood Date: 2007-08-21 Impact factor: 22.113

8. Human Fip1 is a subunit of CPSF that binds to U-rich RNA elements and stimulates poly(A) polymerase.

Authors: Isabelle Kaufmann; Georges Martin; Arno Friedlein; Hanno Langen; Walter Keller
Journal: EMBO J Date: 2004-01-29 Impact factor: 11.598

9. Forced retinoic acid receptor alpha homodimers prime mice for APL-like leukemia.

Authors: Thomas Sternsdorf; Vernon T Phan; Mei Lin Maunakea; Corinne B Ocampo; Jastinder Sohal; Angela Silletto; Francesco Galimi; Michelle M Le Beau; Ronald M Evans; Scott C Kogan
Journal: Cancer Cell Date: 2006-02 Impact factor: 31.743

10. Forced homo-oligomerization of RARalpha leads to transformation of primary hematopoietic cells.

Authors: Colin Kwok; Bernd B Zeisig; Shuo Dong; Chi Wai Eric So
Journal: Cancer Cell Date: 2006-02 Impact factor: 31.743

12 in total

1. R-loop-mediated genome instability in mRNA cleavage and polyadenylation mutants.

Authors: Peter C Stirling; Yujia A Chan; Sean W Minaker; Maria J Aristizabal; Irene Barrett; Payal Sipahimalani; Michael S Kobor; Philip Hieter
Journal: Genes Dev Date: 2012-01-15 Impact factor: 11.361

Review 2. Current views on the genetic landscape and management of variant acute promyelocytic leukemia.

Authors: Xiang Zhang; Jiewen Sun; Wenjuan Yu; Jie Jin
Journal: Biomark Res Date: 2021-05-06

3. A variant of acute promyelocytic leukemia with t(4;17)(q12;q21) showed two different clinical symptoms.

Authors: Takahisa Nakanishi; Aya Nakaya; Yusuke Nishio; Shinya Fujita; Atsushi Satake; Yoshiko Azuma; Yukie Tsubokura; Ryo Saito; Akiko Konishi; Masaaki Hotta; Hideaki Yoshimura; Yoshihiko Kadosaka; Kazuyoshi Ishii; Tomoki Ito; Koji Tsuta; Shosaku Nomura
Journal: Hematol Rep Date: 2019-09-18

Review 4. PLZF-RAR_α, NPM1-RAR_α, and Other Acute Promyelocytic Leukemia Variants: The PETHEMA Registry Experience and Systematic Literature Review.

Authors: Marta Sobas; Maria Carme Talarn-Forcadell; David Martínez-Cuadrón; Lourdes Escoda; María J García-Pérez; Jose Mariz; María J Mela-Osorio; Isolda Fernández; Juan M Alonso-Domínguez; Javier Cornago-Navascués; Gabriela Rodríguez-Macias; María E Amutio; Carlos Rodríguez-Medina; Jordi Esteve; Agnieszka Sokół; Thais Murciano-Carrillo; María J Calasanz; Manuel Barrios; Eva Barragán; Miguel A Sanz; Pau Montesinos
Journal: Cancers (Basel) Date: 2020-05-21 Impact factor: 6.639

5. Successful treatment and integrated genomic analysis of an infant with FIP1L1-RARA fusion-associated myeloid neoplasm.

Authors: Oriana Miltiadous; Kseniya Petrova-Drus; Shipra Kaicker; Susan Mathew; Michael Kluk; Julia T Geyer; Irene Rodriguez-Sanchez; Nancy Bouvier; Giorgio Inghirami; Elliot Stieglitz; Nafa Khedoudja; Ryma Benayed; Michelle Richardson; Wade Anderson; Jamal Benhamida; Daoqi You; Dory Londono; Andrew L Kung; Susan E Prockop; Mikhail Roshal; Yanming Zhang; Neerav Shukla
Journal: Blood Adv Date: 2022-02-22

6. Flow cytometric immunobead assay for fast and easy detection of PML-RARA fusion proteins for the diagnosis of acute promyelocytic leukemia.

Authors: E H A Dekking; V H J van der Velden; R Varro; H Wai; S Böttcher; M Kneba; E Sonneveld; A Koning; N Boeckx; N Van Poecke; P Lucio; A Mendonça; L Sedek; T Szczepański; T Kalina; V Kanderová; P Hoogeveen; J Flores-Montero; M C Chillón; A Orfao; J Almeida; P Evans; M Cullen; A L Noordijk; P M Vermeulen; M T de Man; E P Dixon; W M Comans-Bitter; J J M van Dongen
Journal: Leukemia Date: 2012-05-08 Impact factor: 11.528

10. Myeloid Sarcoma Type of Acute Promyelocytic Leukemia With a Cryptic Insertion of RARA Into FIP1L1: The Clinical Utility of NGS and Bioinformatic Analyses.

Authors: Yongren Wang; Yaoyao Rui; Ying Shen; Jian Li; Poning Liu; Qin Lu; Yongjun Fang
Journal: Front Oncol Date: 2021-06-24 Impact factor: 6.244

FIP1L1/RARA with breakpoint at FIP1L1 intron 13: a variant translocation in acute promyelocytic leukemia.

1. Activation of FIP1L1-PDGFRalpha requires disruption of the juxtamembrane domain of PDGFRalpha and is FIP1L1-independent.

2. Fusion of FIP1L1 and RARA as a result of a novel t(4;17)(q12;q21) in a case of juvenile myelomonocytic leukemia.

3. The seventh pathogenic fusion gene FIP1L1-RARA was isolated from a t(4;17)-positive acute promyelocytic leukemia.

Review 4. Acute promyelocytic leukaemia: novel insights into the mechanisms of cure.

5. A tyrosine kinase created by fusion of the PDGFRA and FIP1L1 genes as a therapeutic target of imatinib in idiopathic hypereosinophilic syndrome.

Review 6. Translocations of the RARalpha gene in acute promyelocytic leukemia.

7. The PRKAR1A gene is fused to RARA in a new variant acute promyelocytic leukemia.

8. Human Fip1 is a subunit of CPSF that binds to U-rich RNA elements and stimulates poly(A) polymerase.

9. Forced retinoic acid receptor alpha homodimers prime mice for APL-like leukemia.

10. Forced homo-oligomerization of RARalpha leads to transformation of primary hematopoietic cells.

1. R-loop-mediated genome instability in mRNA cleavage and polyadenylation mutants.

Review 2. Current views on the genetic landscape and management of variant acute promyelocytic leukemia.

3. A variant of acute promyelocytic leukemia with t(4;17)(q12;q21) showed two different clinical symptoms.

Review 4. PLZF-RAR_α, NPM1-RAR_α, and Other Acute Promyelocytic Leukemia Variants: The PETHEMA Registry Experience and Systematic Literature Review.

5. Successful treatment and integrated genomic analysis of an infant with FIP1L1-RARA fusion-associated myeloid neoplasm.

6. Flow cytometric immunobead assay for fast and easy detection of PML-RARA fusion proteins for the diagnosis of acute promyelocytic leukemia.

Review 7. Classic and Variants APLs, as Viewed from a Therapy Response.

8. [Acute promyelocytic leukemia with STAT3-RARα fusion gene: a case report and literatures review].

Review 9. Acute Promyelocytic Leukemia: A Constellation of Molecular Events around a Single PML-RARA Fusion Gene.

10. Myeloid Sarcoma Type of Acute Promyelocytic Leukemia With a Cryptic Insertion of RARA Into FIP1L1: The Clinical Utility of NGS and Bioinformatic Analyses.

Review 4. Acute promyelocytic leukaemia: novel insights into the mechanisms of cure.

Review 6. Translocations of the RARalpha gene in acute promyelocytic leukemia.

Review 2. Current views on the genetic landscape and management of variant acute promyelocytic leukemia.

Review 4. PLZF-RARα, NPM1-RARα, and Other Acute Promyelocytic Leukemia Variants: The PETHEMA Registry Experience and Systematic Literature Review.

Review 7. Classic and Variants APLs, as Viewed from a Therapy Response.

Review 9. Acute Promyelocytic Leukemia: A Constellation of Molecular Events around a Single PML-RARA Fusion Gene.

Review 4. PLZF-RAR_α, NPM1-RAR_α, and Other Acute Promyelocytic Leukemia Variants: The PETHEMA Registry Experience and Systematic Literature Review.