CONTEXT: Post-ERCP pancreatitis is the most common complication of endoscopic retrograde cholangiopancreatography (ERCP). A simple method of predicting patients who are at risk of developing post-ERCP pancreatitis is needed to allow those at low risk to be discharged on the same day of their procedure. The aim of this study was to confirm that 4-hour post-ERCP serum amylase level is predictive of post-ERCP pancreatitis. PATIENTS: A study of 886 ERCPs performed at a single centre was conducted. MAIN OUTCOME MEASURE: Four-hour amylase level was recorded, along with patient demographics, procedural details, presence of pancreatogram, and morbidity and mortality. RESULTS: Pancreatitis occurred in 4.4% of ERCPs. Hyperamylasaemia was found to be predictive of post-ERCP pancreatitis, with other risk factors being a younger age and pancreatogram. Hyperamylasaemia was also predictive of post-ERCP pancreatitis in the subgroup of patients who had undergone pancreatogram. CONCLUSIONS: The 4-hour amylase level is a useful measure in the prediction of post-ERCP pancreatitis. Patients who have undergone pancreatogram should be admitted if 4-hour amylase level is greater than 2.5 times the upper limit of reference. Patients who have not undergone pancreatogram should be admitted if 4-hour amylase level is greater than 5 times the upper limit of reference.
CONTEXT: Post-ERCP pancreatitis is the most common complication of endoscopic retrograde cholangiopancreatography (ERCP). A simple method of predicting patients who are at risk of developing post-ERCP pancreatitis is needed to allow those at low risk to be discharged on the same day of their procedure. The aim of this study was to confirm that 4-hour post-ERCP serum amylase level is predictive of post-ERCP pancreatitis. PATIENTS: A study of 886 ERCPs performed at a single centre was conducted. MAIN OUTCOME MEASURE: Four-hour amylase level was recorded, along with patient demographics, procedural details, presence of pancreatogram, and morbidity and mortality. RESULTS:Pancreatitis occurred in 4.4% of ERCPs. Hyperamylasaemia was found to be predictive of post-ERCP pancreatitis, with other risk factors being a younger age and pancreatogram. Hyperamylasaemia was also predictive of post-ERCP pancreatitis in the subgroup of patients who had undergone pancreatogram. CONCLUSIONS: The 4-hour amylase level is a useful measure in the prediction of post-ERCP pancreatitis. Patients who have undergone pancreatogram should be admitted if 4-hour amylase level is greater than 2.5 times the upper limit of reference. Patients who have not undergone pancreatogram should be admitted if 4-hour amylase level is greater than 5 times the upper limit of reference.
Authors: Hemant Goyal; Sonali Sachdeva; Syed Ali Amir Sherazi; Shweta Gupta; Abhilash Perisetti; Aman Ali; Saurabh Chandan; Benjamin Tharian; Neil Sharma; Nirav Thosani Journal: Endosc Int Open Date: 2022-07-15
Authors: Ruhua Zheng; Mengjie Chen; Xuying Wang; Bingqiang Li; Ting He; Lei Wang; Guifang Xu; Yuling Yao; Jun Cao; Yonghua Shen; Yi Wang; Hao Zhu; Bin Zhang; Han Wu; Xiaoping Zou; Guoping He Journal: Ann Transl Med Date: 2020-10
Authors: David N Perdigoto; Dário Gomes; Nuno Almeida; Sofia Mendes; Ana Rita Alves; Ernestina Camacho; Luís Tomé Journal: GE Port J Gastroenterol Date: 2018-09-03
Authors: Yeon Kyung Lee; Min Jae Yang; Soon Sun Kim; Choong Kyun Noh; Hyo Jung Cho; Sun Gyo Lim; Jae Chul Hwang; Byung Moo Yoo; Jin Hong Kim Journal: J Korean Med Sci Date: 2017-11 Impact factor: 2.153