PRINCIPLES: Whole body vibration (WBV) is an increasingly popular modality of muscle training, especially in sedentary subjects. We hypothesised that the vigorous muscle contractions elicited by WBV can cause muscle damage expressed as an elevation in muscle enzymes. METHODS: Twenty inactive subjects, ten male and ten female, aged 22.7 ± 2.6, BMI 22.4 ± 2.1 were included based on the absence of regular physical activity as defined by international guidelines, and no history of recent trauma, musculoskeletal pathology, implanted prosthetics, cardiovascular disease or drug intake. The intervention consisted of one bout of high intensity WBV corresponding to a typical training session, involving all the major muscle groups. Plasma levels of muscle enzymes prior to and at 24, 48 and 96 hours post exercise (creatine kinase - CK, MB fraction, troponin I, aminotransferases and lactate dehydrogenase) were measured. In addition, blood lactate was assayed immediately after exercise. Delayed onset muscle soreness (DOMS) was evaluated using a visual analogical scale. RESULTS: Five participants (25%) showed a significant increase in post exercise CK levels (> double of baseline). Maximal value was 3520 U/l. No change was observed in CK-MB or troponin I. Lactate increased to 10.0 ± 2.4 in men and 6.9 ± 2.4 in women. All participants had some degrees of DOMS, without correlation to enzymatic changes. DISCUSSION: WBV can provoke high CK elevation in healthy, medication-free inactive subjects. Such an elevation is transient and harmless, but could be wrongly attributed to drug induced myopathy, as in patients treated with statins. Practitioners should bear this in mind before discontinuing a potential life saving drug.
PRINCIPLES: Whole body vibration (WBV) is an increasingly popular modality of muscle training, especially in sedentary subjects. We hypothesised that the vigorous muscle contractions elicited by WBV can cause muscle damage expressed as an elevation in muscle enzymes. METHODS: Twenty inactive subjects, ten male and ten female, aged 22.7 ± 2.6, BMI 22.4 ± 2.1 were included based on the absence of regular physical activity as defined by international guidelines, and no history of recent trauma, musculoskeletal pathology, implanted prosthetics, cardiovascular disease or drug intake. The intervention consisted of one bout of high intensity WBV corresponding to a typical training session, involving all the major muscle groups. Plasma levels of muscle enzymes prior to and at 24, 48 and 96 hours post exercise (creatine kinase - CK, MB fraction, troponin I, aminotransferases and lactate dehydrogenase) were measured. In addition, blood lactate was assayed immediately after exercise. Delayed onset muscle soreness (DOMS) was evaluated using a visual analogical scale. RESULTS: Five participants (25%) showed a significant increase in post exercise CK levels (> double of baseline). Maximal value was 3520 U/l. No change was observed in CK-MB or troponin I. Lactate increased to 10.0 ± 2.4 in men and 6.9 ± 2.4 in women. All participants had some degrees of DOMS, without correlation to enzymatic changes. DISCUSSION: WBV can provoke high CK elevation in healthy, medication-free inactive subjects. Such an elevation is transient and harmless, but could be wrongly attributed to drug induced myopathy, as in patients treated with statins. Practitioners should bear this in mind before discontinuing a potential life saving drug.
Authors: Yufan Chu; Qiming Wang; Muyan Chu; Baofeng Geng; Huanguang Jia; Xiaolong Li; Tao Lv; Suyi Jiang Journal: Int J Environ Res Public Health Date: 2022-06-20 Impact factor: 4.614
Authors: Cid André Fidelis de Paula Gomes; Ernesto Cesar Pinto Leal-Junior; Daniela Aparecida Biasotto-Gonzalez; Yasmin El-Hage; Fabiano Politti; Tabajara de Oliveira Gonzalez; Almir Vieira Dibai-Filho; Adriano Rodrigues de Oliveira; Marcelo Frigero; Fernanda Colella Antonialli; Adriane Aver Vanin; Paulo de Tarso Camillo de Carvalho Journal: Trials Date: 2014-04-09 Impact factor: 2.279
Authors: Milena de Oliveira Bravo Monteiro; Danúbia da Cunha de Sá-Caputo; Eloá Moreira-Marconi; Éric Heleno Freire Ferreira Frederico; Cintia Renata de Sousa-Gonçalves; Luciana Camargo Bernardo; Carlos Alberto Sampaio Guimarães; Mario Bernardo-Filho Journal: Afr J Tradit Complement Altern Med Date: 2017-07-07