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Literature DB >> 21732670

Molecular tumor clocks to study the evolution of drug resistance.

Abstract

It is likely that drug resistance evolves after transformation. Exactly how these resistant cells arise is uncertain. This review outlines how the evolution of individual human cancers may be inferred by comparing genomic variation from different parts of the same tumor. The past of a tumor may help predict its responses to chemotherapy.

Entities: Chemical Disease Gene Species

Mesh：

Year: 2011 PMID： 21732670 PMCID： PMC4142061 DOI： 10.1021/mp200256n

Source DB: PubMed Journal: Mol Pharm ISSN： 1543-8384 Impact factor: 4.939

26 in total

1. Mutation selection and the natural history of cancer.

Authors: J Cairns
Journal: Nature Date: 1975-05-15 Impact factor: 49.962

Review 2. The modern molecular clock.

Authors: Lindell Bromham; David Penny
Journal: Nat Rev Genet Date: 2003-03 Impact factor: 53.242

3. A progression puzzle.

Authors: René Bernards; Robert A Weinberg
Journal: Nature Date: 2002-08-22 Impact factor: 49.962

Review 4. Stem cells, cancer, and cancer stem cells.

Authors: T Reya; S J Morrison; M F Clarke; I L Weissman
Journal: Nature Date: 2001-11-01 Impact factor: 49.962

5. A Gompertzian model of human breast cancer growth.

Authors: L Norton
Journal: Cancer Res Date: 1988-12-15 Impact factor: 12.701

Review 6. Tumor heterogeneity.

Authors: G H Heppner
Journal: Cancer Res Date: 1984-06 Impact factor: 12.701

7. Tumour evolution inferred by single-cell sequencing.

Authors: Nicholas Navin; Jude Kendall; Jennifer Troge; Peter Andrews; Linda Rodgers; Jeanne McIndoo; Kerry Cook; Asya Stepansky; Dan Levy; Diane Esposito; Lakshmi Muthuswamy; Alex Krasnitz; W Richard McCombie; James Hicks; Michael Wigler
Journal: Nature Date: 2011-03-13 Impact factor: 49.962

8. Defective mismatch repair in extracts of colorectal and endometrial cancer cell lines exhibiting microsatellite instability.

Authors: A Umar; J C Boyer; D C Thomas; D C Nguyen; J I Risinger; J Boyd; Y Ionov; M Perucho; T A Kunkel
Journal: J Biol Chem Date: 1994-05-20 Impact factor: 5.157

Molecular tumor clocks to study the evolution of drug resistance.

1. Mutation selection and the natural history of cancer.

Review 2. The modern molecular clock.

3. A progression puzzle.

Review 4. Stem cells, cancer, and cancer stem cells.

5. A Gompertzian model of human breast cancer growth.

Review 6. Tumor heterogeneity.

7. Tumour evolution inferred by single-cell sequencing.

8. Defective mismatch repair in extracts of colorectal and endometrial cancer cell lines exhibiting microsatellite instability.

9. The genetic origin of drug resistance in neoplasms: implications for systemic therapy.

10. A mathematic model for relating the drug sensitivity of tumors to their spontaneous mutation rate.

Review 1. The structural basis for cancer treatment decisions.

2. MicroRNA-200c delivered by solid lipid nanoparticles enhances the effect of paclitaxel on breast cancer stem cell.