Effects of Ginkgo biloba extract on free radical metabolism of liver in mice during endurance exercise.

This study investigated the effect of Ginkgo biloba extract on Free Radical Metabolism of Liver in mice during endurance exercise. Forty-eight mice were divided into the quiet group and the exercised group. And the two groups were both grouped again, including the control group and the drug-treated group. After exhaustive exercise, the exercised groups were subdivided into the immediate group and the recovery group. The swimming time to exhaustion significantly prolonged in the exercised drug-treated group as compared with the exercised control group (P < 0.05); The SOD activity of drug-treated groups significantly increased (P < 0.05) as compared with the control groups and MDA content was significantly lower (P < 0.05). The SOD activity and MDA content of exercised control groups significantly increased (P < 0.05) as compared with the quiet control group. The SOD activity and MDA content of exercised drug-treated groups significantly increased (P < 0.05) as compared with the quiet drug-treated group. The results indicated that Ginkgo biloba extract can obviously increase the body's endurance exercise capacity in mice and delay fatigue; Ginkgo biloba extract can help to increase the activity of the antioxidant enzymes in liver tissue, reduce the lipid peroxidation injury in liver tissue caused by free radicals, improve athletic ability, and promote the recovery process after exercise in mice.