Literature DB >> 21726218

The interleukin-17 cytokine family: critical players in host defence and inflammatory diseases.

Rajita Pappu1, Vladimir Ramirez-Carrozzi, Arivazhagan Sambandam.   

Abstract

The interleukin-17 (IL-17) cytokines, IL-17A to IL-17F, are emerging as critical players in host defence responses and inflammatory diseases. Substantial data support the role of these proteins in innate and adaptive immunity. Of these family members, IL-17A, IL-17F and IL-17E have been the best studied. Both IL-17A and IL-17F contribute to the host response to extracellular bacteria and fungi, and IL-17E has been shown to play a role in parasitic infections. In addition, numerous pre-clinical and clinical studies link these proteins to the pathogenesis of inflammatory diseases, and a number of therapeutic programmes targeting these family members are in clinical development. This review will highlight the cellular sources, receptors/target cells, and role in inflammation of these and the less-characterized family members, IL-17B, IL-17C and IL-17D.
© 2011 Genentech, Inc. Immunology © 2011 Blackwell Publishing Ltd.

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Year:  2011        PMID： 21726218      PMCID： PMC3173690          DOI： 10.1111/j.1365-2567.2011.03465.x

Source DB:  PubMed          Journal:  Immunology        ISSN： 0019-2805            Impact factor:   7.397


  115 in total

1.  Development, cytokine profile and function of human interleukin 17-producing helper T cells.

Authors:  Nicholas J Wilson; Katia Boniface; Jason R Chan; Brent S McKenzie; Wendy M Blumenschein; Jeanine D Mattson; Beth Basham; Kathleen Smith; Taiying Chen; Franck Morel; Jean-Claude Lecron; Robert A Kastelein; Daniel J Cua; Terrill K McClanahan; Edward P Bowman; Rene de Waal Malefyt
Journal:  Nat Immunol       Date:  2007-08-05       Impact factor: 25.606

2.  Identification of the IL-17 receptor related molecule IL-17RC as the receptor for IL-17F.

Authors:  Rolf E Kuestner; David W Taft; Aaron Haran; Cameron S Brandt; Ty Brender; Karen Lum; Brandon Harder; Shannon Okada; Craig D Ostrander; James L Kreindler; Shean J Aujla; Brian Reardon; Margaret Moore; Pamela Shea; Randall Schreckhise; Thomas R Bukowski; Scott Presnell; Patricia Guerra-Lewis; Julia Parrish-Novak; Jeff L Ellsworth; Stephen Jaspers; Katherine E Lewis; Mark Appleby; Jay K Kolls; Mark Rixon; James W West; Zeren Gao; Steven D Levin
Journal:  J Immunol       Date:  2007-10-15       Impact factor: 5.422

3.  Interleukin-23 (IL-23)-IL-17 cytokine axis in murine Pneumocystis carinii infection.

Authors:  Xiaowen L Rudner; Kyle I Happel; Erana A Young; Judd E Shellito
Journal:  Infect Immun       Date:  2007-04-02       Impact factor: 3.441

4.  Inflammatory responses induced by interleukin-17 family members in human colonic subepithelial myofibroblasts.

Authors:  Yuhki Yagi; Akira Andoh; Osamu Inatomi; Tomoyuki Tsujikawa; Yoshihide Fujiyama
Journal:  J Gastroenterol       Date:  2007-09-25       Impact factor: 7.527

5.  IL-17B and IL-17C are associated with TNF-alpha production and contribute to the exacerbation of inflammatory arthritis.

Authors:  Yumi Yamaguchi; Keishi Fujio; Hirofumi Shoda; Akiko Okamoto; Nelson H Tsuno; Koki Takahashi; Kazuhiko Yamamoto
Journal:  J Immunol       Date:  2007-11-15       Impact factor: 5.422

6.  A novel heterodimeric cytokine consisting of IL-17 and IL-17F regulates inflammatory responses.

Authors:  Seon Hee Chang; Chen Dong
Journal:  Cell Res       Date:  2007-05       Impact factor: 25.617

7.  An IL-17F/A heterodimer protein is produced by mouse Th17 cells and induces airway neutrophil recruitment.

Authors:  Spencer C Liang; Andrew J Long; Frann Bennett; Matthew J Whitters; Riyez Karim; Mary Collins; Samuel J Goldman; Kyriaki Dunussi-Joannopoulos; Cara M M Williams; Jill F Wright; Lynette A Fouser
Journal:  J Immunol       Date:  2007-12-01       Impact factor: 5.422

8.  Essential autocrine regulation by IL-21 in the generation of inflammatory T cells.

Authors:  Roza Nurieva; Xuexian O Yang; Gustavo Martinez; Yongliang Zhang; Athanasia D Panopoulos; Li Ma; Kimberly Schluns; Qiang Tian; Stephanie S Watowich; Anton M Jetten; Chen Dong
Journal:  Nature       Date:  2007-06-20       Impact factor: 49.962

9.  IL-6 programs T(H)-17 cell differentiation by promoting sequential engagement of the IL-21 and IL-23 pathways.

Authors:  Liang Zhou; Ivaylo I Ivanov; Rosanne Spolski; Roy Min; Kevin Shenderov; Takeshi Egawa; David E Levy; Warren J Leonard; Dan R Littman
Journal:  Nat Immunol       Date:  2007-06-20       Impact factor: 25.606

10.  IL-25 augments type 2 immune responses by enhancing the expansion and functions of TSLP-DC-activated Th2 memory cells.

Authors:  Yui-Hsi Wang; Pornpimon Angkasekwinai; Ning Lu; Kui Shin Voo; Kazuhiko Arima; Shino Hanabuchi; Andreas Hippe; Chris J Corrigan; Chen Dong; Bernhard Homey; Zhengbin Yao; Sun Ying; David P Huston; Yong-Jun Liu
Journal:  J Exp Med       Date:  2007-07-16       Impact factor: 14.307
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  94 in total

Review 1.  [A decade of biologics in dermatology].

Authors:  G Wozel; M Meurer
Journal:  Hautarzt       Date:  2012-04       Impact factor: 0.751

Review 2.  The amphioxus genome provides unique insight into the evolution of immunity.

Authors:  Larry J Dishaw; Robert N Haire; Gary W Litman
Journal:  Brief Funct Genomics       Date:  2012-03-07       Impact factor: 4.241

Review 3.  Regulation of intestinal epithelial permeability by tight junctions.

Authors:  Takuya Suzuki
Journal:  Cell Mol Life Sci       Date:  2012-07-11       Impact factor: 9.261

4.  Delayed resolution of lung inflammation in Il-1rn-/- mice reflects elevated IL-17A/granulocyte colony-stimulating factor expression.

Authors:  Kristin M Hudock; Yuhong Liu; Junjie Mei; Roberta C Marino; Jason E Hale; Ning Dai; G Scott Worthen
Journal:  Am J Respir Cell Mol Biol       Date:  2012-05-16       Impact factor: 6.914

5.  Comparative proteomic analysis reveals activation of mucosal innate immune signaling pathways during cholera.

Authors:  Crystal N Ellis; Regina C LaRocque; Taher Uddin; Bryan Krastins; Leslie M Mayo-Smith; David Sarracino; Elinor K Karlsson; Atiqur Rahman; Tahmina Shirin; Taufiqur R Bhuiyan; Fahima Chowdhury; Ashraful Islam Khan; Edward T Ryan; Stephen B Calderwood; Firdausi Qadri; Jason B Harris
Journal:  Infect Immun       Date:  2015-01-05       Impact factor: 3.441

6.  IL-17 Receptor Signaling in the Lung Epithelium Is Required for Mucosal Chemokine Gradients and Pulmonary Host Defense against K. pneumoniae.

Authors:  Kong Chen; Taylor Eddens; Giraldina Trevejo-Nunez; Emily E Way; Waleed Elsegeiny; David M Ricks; Abhishek V Garg; Carla J Erb; Meihua Bo; Ting Wang; Wei Chen; Janet S Lee; Sarah L Gaffen; Jay K Kolls
Journal:  Cell Host Microbe       Date:  2016-10-27       Impact factor: 21.023

7.  A role for interleukin-17A in modulating intracellular survival of Mycobacterium bovis bacillus Calmette-Guérin in murine macrophages.

Authors:  Wai Lim Ling; Liang Jie Wang; John C H Pong; Allan S Y Lau; James C B Li
Journal:  Immunology       Date:  2013-11       Impact factor: 7.397

8.  The nature of innate and adaptive interleukin-17A responses in sham or bacterial inoculation.

Authors:  Deborah L W Chong; Rebecca J Ingram; Daniel E Lowther; Roshell Muir; Shiranee Sriskandan; Daniel M Altmann
Journal:  Immunology       Date:  2012-07       Impact factor: 7.397

9.  Interleukin-10 (IL-10) inhibits Borrelia burgdorferi-induced IL-17 production and attenuates IL-17-mediated Lyme arthritis.

Authors:  Emily S Hansen; Velinka Medić; Joseph Kuo; Thomas F Warner; Ronald F Schell; Dean T Nardelli
Journal:  Infect Immun       Date:  2013-09-16       Impact factor: 3.441

10.  Biopsychological stress factors in BRCA mutation carriers.

Authors:  Lari Wenzel; Kathyrn Osann; Jenny Lester; Raluca Kurz; Susie Hsieh; Edward L Nelson; Beth Karlan
Journal:  Psychosomatics       Date:  2012 Nov-Dec       Impact factor: 2.386
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