| Literature DB >> 2172540 |
C C Tsai1, K E Follis, K Snyder, S Windsor, M E Thouless, L Kuller, W R Morton.
Abstract
Pregnant macaques were used as a natural model for maternal-infant transmission of SRV-2 retrovirus. Fifty-one pregnant females were placed into one of four virus/antibody groups. Nonviremic mothers produced 100% virus-negative offspring at birth. In contrast, viremic mothers produced offspring which were 17% virus-negative and 83% virus-positive at birth. SRV-2 infection occurred principally in utero by the transplacental route. Infants born to viremic mothers exhibited low birth weight, prematurity, high perinatal death, and increased incidence of SAIDS.Entities:
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Year: 1990 PMID: 2172540
Source DB: PubMed Journal: J Med Primatol ISSN: 0047-2565 Impact factor: 0.667