| Literature DB >> 20615522 |
Chih-Ling Zao1, Karyn Armstrong, Lisa Tomanek, Anthony Cooke, Ron Berger, J Scot Estep, Preston A Marx, Jessica Satkoski Trask, David G Smith, Joann L Yee, Nicholas W Lerche.
Abstract
At least 5 serotypes of exogenous simian retrovirus type D (SRV/D) have been found in nonhuman primates, but only SRV-1, 2 and 3 have been completely sequenced. SRV-4 was recovered once from cynomolgus macaques in California in 1984, but its genome sequences are unknown. Here we report the second identification of SRV-4 and its complete genome from infected cynomolgus macaques with Indochinese and Indonesian/Indochinese mixed ancestry. Phylogenetic analysis demonstrated that SRV-4 was distantly related to SRV-1, 2, 3, 5, 6 and 7. SRV/D-T, a new SRV/D recovered in 2005 from cynomolgus monkeys at Tsukuba Primate Center in Japan, clustered with the SRV-4 isolates from California and Texas and was shown to be another occurrence of SRV-4 infection. The repeated occurrence of SRV-4 in cynomolgus monkeys in different areas of the world and across 25years suggests that this species is the natural host of SRV-4. Copyright 2010 Elsevier Inc. All rights reserved.Entities:
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Year: 2010 PMID： 20615522 PMCID： PMC2941434 DOI： 10.1016/j.virol.2010.06.028
Source DB: PubMed Journal: Virology ISSN： 0042-6822 Impact factor: 3.616