Literature DB >> 21719143

Signet ring cell adenocarcinoma of the lung with an EML4-ALK fusion gene mimicking mucinous (colloid) adenocarcinoma: a case report.

Taro Ohba1, Kenji Sugio, Takuro Kometani, Masafumi Yamaguchi, Motoharu Hamatake, Kaname Nosaki, Hiroaki Takeoka, Hiromoto Kitajima, Fumihiko Hirai, Takashi Seto, Kenichi Taguchi, Kenichi Nishiyama, Yoshitaka Shida, Yukito Ichinose.   

Abstract

We herein report a case of signet ring cell adenocarcinoma of the lung with an EML4-ALK fusion gene mimicking mucinous (colloid) adenocarcinoma. A 79-year-old female presented with a pulmonary tumor located in the right lower lobe measuring 21 mm in size. A right lower lobectomy was performed. The postoperative pathological examination revealed signet ring cell carcinoma with abundant mucin pools, and a multiplex RT-PCR analysis revealed the variant 2 inversion of the EML4-ALK gene.
Copyright © 2011 Elsevier Ireland Ltd. All rights reserved.

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Year:  2011        PMID: 21719143     DOI: 10.1016/j.lungcan.2011.05.016

Source DB:  PubMed          Journal:  Lung Cancer        ISSN: 0169-5002            Impact factor:   5.705


  2 in total

1.  Ocular metastasis of lung adenocarcinoma with ELM4-ALK translocation: A case report with a review of the literature.

Authors:  Kailun Jiang; Seymour Brownstein; Harmanjatinder S Sekhon; Scott A Laurie; Kay Lam; Steven Gilberg; William Britton
Journal:  Saudi J Ophthalmol       Date:  2013-07

2.  Clinicopathological features of younger (aged ≤ 50 years) lung adenocarcinoma patients harboring the EML4-ALK fusion gene.

Authors:  Takuro Kometani; Kenji Sugio; Atsushi Osoegawa; Takashi Seto; Yukito Ichinose
Journal:  Thorac Cancer       Date:  2018-03-08       Impact factor: 3.500

  2 in total

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