Literature DB >> 21717370

HIV-1-induced alterations of claudin-5 expression at the blood-brain barrier level.

Ibolya E András, Michal Toborek.   

Abstract

HIV-1 crosses the blood-brain barrier (BBB) early in the course of systemic infection and resides in brain macrophages and microglia. The integrity of the brain endothelium is regulated by intercellular tight junctions, which also play a critical role in HIV-1-entry into the brain. Disruption of tight junctions, including changes in claudin-5 expression, is common in HIV-1-infected patients. Recent evidence indicates that both exposure to HIV-1 and HIV-1 specific proteins, such as Tat protein, can contribute to alterations of expression and distribution of claudin-5 in brain endothelial cells and brain microvessels.

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Year:  2011        PMID： 21717370      PMCID： PMC3292788          DOI： 10.1007/978-1-61779-185-7_26

Source DB:  PubMed          Journal:  Methods Mol Biol        ISSN： 1064-3745


  27 in total

1.  Monocyte infiltration is highly associated with loss of the tight junction protein zonula occludens in HIV-1-associated dementia.

Authors:  L A Boven; J Middel; J Verhoef; C J De Groot; H S Nottet
Journal:  Neuropathol Appl Neurobiol       Date:  2000-08       Impact factor: 8.090

2.  Selective CXCR4 antagonism by Tat: implications for in vivo expansion of coreceptor use by HIV-1.

Authors:  H Xiao; C Neuveut; H L Tiffany; M Benkirane; E A Rich; P M Murphy; K T Jeang
Journal:  Proc Natl Acad Sci U S A       Date:  2000-10-10       Impact factor: 11.205

Review 3.  Ras proteins: different signals from different locations.

Authors:  John F Hancock
Journal:  Nat Rev Mol Cell Biol       Date:  2003-05       Impact factor: 94.444

4.  Blood-brain barrier tight junction disruption in human immunodeficiency virus-1 encephalitis.

Authors:  L M Dallasta; L A Pisarov; J E Esplen; J V Werley; A V Moses; J A Nelson; C L Achim
Journal:  Am J Pathol       Date:  1999-12       Impact factor: 4.307

5.  HIV-Tat protein induces oxidative and inflammatory pathways in brain endothelium.

Authors:  Michal Toborek; Yong Woo Lee; Hong Pu; Andrzej Malecki; Govinder Flora; Rosario Garrido; Bernhard Hennig; Hans-Christian Bauer; Avindra Nath
Journal:  J Neurochem       Date:  2003-01       Impact factor: 5.372

6.  Molecular determinants for cellular uptake of Tat protein of human immunodeficiency virus type 1 in brain cells.

Authors:  M Ma; A Nath
Journal:  J Virol       Date:  1997-03       Impact factor: 5.103

Review 7.  Neurobiological aspects of human immunodeficiency virus infection: neurotoxic mechanisms.

Authors:  A Nath; J Geiger
Journal:  Prog Neurobiol       Date:  1998-01       Impact factor: 11.685

8.  The angiogenesis induced by HIV-1 tat protein is mediated by the Flk-1/KDR receptor on vascular endothelial cells.

Authors:  A Albini; R Soldi; D Giunciuglio; E Giraudo; R Benelli; L Primo; D Noonan; M Salio; G Camussi; W Rockl; F Bussolino
Journal:  Nat Med       Date:  1996-12       Impact factor: 53.440

9.  Caveolin-1 regulates human immunodeficiency virus-1 Tat-induced alterations of tight junction protein expression via modulation of the Ras signaling.

Authors:  Yu Zhong; Eric J Smart; Babette Weksler; Pierre-Olivier Couraud; Bernhard Hennig; Michal Toborek
Journal:  J Neurosci       Date:  2008-07-30       Impact factor: 6.167

10.  Human immunodeficiency virus type 1 Tat regulates endothelial cell actin cytoskeletal dynamics through PAK1 activation and oxidant production.

Authors:  Ru Feng Wu; Ying Gu; You Cheng Xu; Stefania Mitola; Federico Bussolino; Lance S Terada
Journal:  J Virol       Date:  2004-01       Impact factor: 5.103
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  18 in total

Review 1.  Tight junction in blood-brain barrier: an overview of structure, regulation, and regulator substances.

Authors:  Wei-Ye Liu; Zhi-Bin Wang; Li-Chao Zhang; Xin Wei; Ling Li
Journal:  CNS Neurosci Ther       Date:  2012-06-12       Impact factor: 5.243

2.  Transcriptional profile of HIV-induced nuclear translocation of amyloid β in brain endothelial cells.

Authors:  Ibolya E András; Evadnie Rampersaud; Sung Yong Eum; Michal Toborek
Journal:  Arch Med Res       Date:  2014-11-13       Impact factor: 2.235

3.  Tembusu Virus entering the central nervous system caused nonsuppurative encephalitis without disrupting the blood-brain barrier.

Authors:  Sheng Yang; Yufei Huang; Yonghong Shi; Xuebing Bai; Ping Yang; Qiusheng Chen
Journal:  J Virol       Date:  2021-01-20       Impact factor: 5.103

4.  Viral Infection of the Central Nervous System and Neuroinflammation Precede Blood-Brain Barrier Disruption during Japanese Encephalitis Virus Infection.

Authors:  Fang Li; Yueyun Wang; Lan Yu; Shengbo Cao; Ke Wang; Jiaolong Yuan; Chong Wang; Kunlun Wang; Min Cui; Zhen F Fu
Journal:  J Virol       Date:  2015-03-11       Impact factor: 5.103

Review 5.  Neurotoxicity in the Post-HAART Era: Caution for the Antiretroviral Therapeutics.

Authors:  Ankit Shah; Mohitkumar R Gangwani; Nitish S Chaudhari; Alexy Glazyrin; Hari K Bhat; Anil Kumar
Journal:  Neurotox Res       Date:  2016-06-30       Impact factor: 3.911

6.  The Noncompetitive AMPAR Antagonist Perampanel Abrogates Brain Endothelial Cell Permeability in Response to Ischemia: Involvement of Claudin-5.

Authors:  Jian-Meng Lv; Xiao-Min Guo; Bo Chen; Qi Lei; Ya-Juan Pan; Qian Yang
Journal:  Cell Mol Neurobiol       Date:  2015-08-26       Impact factor: 5.046

7.  HIV-1 stimulates nuclear entry of amyloid beta via dynamin dependent EEA1 and TGF-β/Smad signaling.

Authors:  Ibolya E András; Michal Toborek
Journal:  Exp Cell Res       Date:  2014-01-31       Impact factor: 3.905

Review 8.  HIV and Alzheimer's disease: complex interactions of HIV-Tat with amyloid β peptide and Tau protein.

Authors:  Alina Hategan; Eliezer Masliah; Avindra Nath
Journal:  J Neurovirol       Date:  2019-04-23       Impact factor: 2.643

9.  Brain transcriptome-wide screen for HIV-1 Nef protein interaction partners reveals various membrane-associated proteins.

Authors:  Ellen C Kammula; Jessica Mötter; Alexandra Gorgels; Esther Jonas; Silke Hoffmann; Dieter Willbold
Journal:  PLoS One       Date:  2012-12-17       Impact factor: 3.240

10.  The hCMEC/D3 cell line as a model of the human blood brain barrier.

Authors:  Babette Weksler; Ignacio A Romero; Pierre-Olivier Couraud
Journal:  Fluids Barriers CNS       Date:  2013-03-26
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