Literature DB >> 21716451

Extended focus high-speed swept source OCT with self-reconstructive illumination.

Cedric Blatter1, Branislav Grajciar, Christoph M Eigenwillig, Wolfgang Wieser, Benjamin R Biedermann, Robert Huber, Rainer A Leitgeb.   

Abstract

We present a Bessel beam illumination FDOCT setup using a FDML Swept Source at 1300 nm with up to 440 kHz A-scan rate, and discuss its advantages for structural and functional imaging of highly scattering samples. An extended focus is achieved due to the Bessel beam that preserves its lateral extend over a large depth range. Furthermore, Bessel beams exhibit a self-reconstruction property that allows imaging even behind obstacles such as hairs on skin. Decoupling the illumination from the gaussian detection increases the global sensitivity and enables dark field imaging. Dark field imaging is useful to avoid strong reflexes from the sample surface that adversely affect the sensitivity due to the limited dynamic range of high speed 8 bit acquisition cards. In addition the possibility of contrasting capillaries with high sensitivity is shown, using inter-B-scan speckle variance analysis. We demonstrate intrinsic advantages of the extended focus configuration, in particular the reduction of the phase decorrelation effect below vessels leading to improved axial vessel definition.

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Year:  2011        PMID: 21716451     DOI: 10.1364/OE.19.012141

Source DB:  PubMed          Journal:  Opt Express        ISSN: 1094-4087            Impact factor:   3.894


  19 in total

1.  Ultrahigh speed spectral-domain optical coherence microscopy.

Authors:  Hsiang-Chieh Lee; Jonathan J Liu; Yuri Sheikine; Aaron D Aguirre; James L Connolly; James G Fujimoto
Journal:  Biomed Opt Express       Date:  2013-07-01       Impact factor: 3.732

2.  Measurement of dynamic cell-induced 3D displacement fields in vitro for traction force optical coherence microscopy.

Authors:  Jeffrey A Mulligan; François Bordeleau; Cynthia A Reinhart-King; Steven G Adie
Journal:  Biomed Opt Express       Date:  2017-01-27       Impact factor: 3.732

3.  Volumetric optical coherence microscopy with a high space-bandwidth-time product enabled by hybrid adaptive optics.

Authors:  Siyang Liu; Jeffrey A Mulligan; Steven G Adie
Journal:  Biomed Opt Express       Date:  2018-06-15       Impact factor: 3.732

4.  Structured interference optical coherence tomography.

Authors:  Ji Yi; Qing Wei; Hao F Zhang; Vadim Backman
Journal:  Opt Lett       Date:  2012-08-01       Impact factor: 3.776

5.  Dermoscopy guided dark-field multi-functional optical coherence tomography.

Authors:  Soonjae Kwon; Yeoreum Yoon; Bumju Kim; Won Hyuk Jang; Byungho Oh; Kee Yang Chung; Ki Hean Kim
Journal:  Biomed Opt Express       Date:  2017-02-06       Impact factor: 3.732

6.  Multifocal interferometric synthetic aperture microscopy.

Authors:  Yang Xu; Xiong Kai Benjamin Chng; Steven G Adie; Stephen A Boppart; P Scott Carney
Journal:  Opt Express       Date:  2014-06-30       Impact factor: 3.894

7.  Parallelized multi-graphics processing unit framework for high-speed Gabor-domain optical coherence microscopy.

Authors:  Patrice Tankam; Anand P Santhanam; Kye-Sung Lee; Jungeun Won; Cristina Canavesi; Jannick P Rolland
Journal:  J Biomed Opt       Date:  2014-07       Impact factor: 3.170

8.  Extended focal depth Fourier domain optical coherence microscopy with a Bessel-beam - LP02 mode - from a higher order mode fiber.

Authors:  Dipankar Sen; Anton Classen; Alma Fernández; Lars Grüner-Nielsen; Holly C Gibbs; Shahriar Esmaeili; Philip Hemmer; Andrius Baltuska; Alexei V Sokolov; Rainer A Leitgeb; Aart J Verhoef
Journal:  Biomed Opt Express       Date:  2021-11-05       Impact factor: 3.732

9.  Gabor domain optical coherence microscopy combined with laser scanning confocal fluorescence microscopy.

Authors:  Changsik Yoon; Yue Qi; Humberto Mestre; Cristina Canavesi; Olivia J Marola; Andrea Cogliati; Maiken Nedergaard; Richard T Libby; Jannick P Rolland
Journal:  Biomed Opt Express       Date:  2019-11-14       Impact factor: 3.732

10.  In situ structural and microangiographic assessment of human skin lesions with high-speed OCT.

Authors:  Cedric Blatter; Jessika Weingast; Aneesh Alex; Branislav Grajciar; Wolfgang Wieser; Wolfgang Drexler; Robert Huber; Rainer A Leitgeb
Journal:  Biomed Opt Express       Date:  2012-09-24       Impact factor: 3.732

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