| Literature DB >> 21708481 |
Mario Pérez-Sayáns1, José Manuel Suárez-Peñaranda, Gayoso-Diz Pilar, Francisco Barros-Angueira, José Manuel Gándara-Rey, Abel García-García.
Abstract
The influence of c-myc in the carcinogenic process has been previously described although in the specific case of oral tumors it has been poorly tested. Myc proteins are a family of proto-oncogenes involved in the cell proliferation regulation, differentiation and apoptosis. The goal of this paper is to describe the functions of c-myc and its role as oncogene, assessing its expression by immunohistochemistry and genetic amplification studies, and studying its relationship with tumoral clinical and pathological variables, and describing genetic and molecular interactions in OSCC.Entities:
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Year: 2011 PMID: 21708481 DOI: 10.1016/j.oraloncology.2011.05.016
Source DB: PubMed Journal: Oral Oncol ISSN: 1368-8375 Impact factor: 5.337