Literature DB >> 21708481

What real influence does the proto-oncogene c-myc have in OSCC behavior?

Mario Pérez-Sayáns1, José Manuel Suárez-Peñaranda, Gayoso-Diz Pilar, Francisco Barros-Angueira, José Manuel Gándara-Rey, Abel García-García.   

Abstract

The influence of c-myc in the carcinogenic process has been previously described although in the specific case of oral tumors it has been poorly tested. Myc proteins are a family of proto-oncogenes involved in the cell proliferation regulation, differentiation and apoptosis. The goal of this paper is to describe the functions of c-myc and its role as oncogene, assessing its expression by immunohistochemistry and genetic amplification studies, and studying its relationship with tumoral clinical and pathological variables, and describing genetic and molecular interactions in OSCC.
Copyright © 2011 Elsevier Ltd. All rights reserved.

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Year:  2011        PMID: 21708481     DOI: 10.1016/j.oraloncology.2011.05.016

Source DB:  PubMed          Journal:  Oral Oncol        ISSN: 1368-8375            Impact factor:   5.337


  10 in total

1.  Low expression of miR-let-7a promotes cell growth and invasion through the regulation of c-Myc in oral squamous cell carcinoma.

Authors:  Chunyang Luo; Jiyong Zhang; Yi Zhang; Xiao Zhang; Yinan Chen; Weimin Fan
Journal:  Cell Cycle       Date:  2020-06-28       Impact factor: 4.534

2.  Potential role of the OVOL1-OVOL2 axis and c-Myc in the progression of cutaneous squamous cell carcinoma.

Authors:  Takamichi Ito; Gaku Tsuji; Fumitaka Ohno; Takeshi Nakahara; Hiroshi Uchi; Masutaka Furue
Journal:  Mod Pathol       Date:  2017-03-24       Impact factor: 7.842

3.  Sendai virus-mediated gene transfer of the c-myc suppressor far-upstream element-binding protein-interacting repressor suppresses head and neck cancer.

Authors:  N Tanaka; K Araki; D Mizokami; Y Miyagawa; T Yamashita; M Tomifuji; Y Ueda; M Inoue; K Matsushita; F Nomura; H Shimada; A Shiotani
Journal:  Gene Ther       Date:  2015-01-15       Impact factor: 5.250

4.  Amplification of EGFR and cyclin D1 genes associated with human papillomavirus infection in oral squamous cell carcinoma.

Authors:  Jureeporn Chuerduangphui; Chamsai Pientong; Natcha Patarapadungkit; Apinya Chotiyano; Patravoot Vatanasapt; Bunkerd Kongyingyoes; Supannee Promthet; Piyawut Swangphon; Sureewan Bumrungthai; Charinya Pimson; Tipaya Ekalaksananan
Journal:  Med Oncol       Date:  2017-07-24       Impact factor: 3.064

5.  Identification of a Novel Proto-oncogenic Network in Head and Neck Squamous Cell Carcinoma.

Authors:  Smitha R Georgy; Michael Cangkrama; Seema Srivastava; Darren Partridge; Alana Auden; Sebastian Dworkin; Catriona A McLean; Stephen M Jane; Charbel Darido
Journal:  J Natl Cancer Inst       Date:  2015-06-10       Impact factor: 13.506

6.  CXCL13 activation of c-Myc induces RANK ligand expression in stromal/preosteoblast cells in the oral squamous cell carcinoma tumor-bone microenvironment.

Authors:  Y Sambandam; K Sundaram; A Liu; K L Kirkwood; W L Ries; S V Reddy
Journal:  Oncogene       Date:  2012-02-13       Impact factor: 9.867

7.  Bcl-2 and c-Myc expression in oral dysplasia and oral squamous cell carcinoma: An immunohistochemical study to assess tumor progression.

Authors:  N Pallavi; Govind Raj K Nalabolu; Santhosh Kumar S Hiremath
Journal:  J Oral Maxillofac Pathol       Date:  2018 Sep-Dec

Review 8.  Long non-coding RNAs in Oral squamous cell carcinoma: biologic function, mechanisms and clinical implications.

Authors:  Lei Zhang; Xiang Meng; Xin-Wei Zhu; Deng-Cheng Yang; Ran Chen; Yong Jiang; Tao Xu
Journal:  Mol Cancer       Date:  2019-05-27       Impact factor: 27.401

9.  Silencing of LncRNA AFAP1-AS1 Inhibits Cell Proliferation in Oral Squamous Cancer by Suppressing CCNA2.

Authors:  Tao Li; Duanqin Liu; Chenglong Li; Lu Ru; Xuixia Wang
Journal:  Cancer Manag Res       Date:  2021-10-15       Impact factor: 3.989

10.  Novel cytological model for the identification of early oral cancer diagnostic markers: The carcinoma sequence model.

Authors:  Masami Kawaharada; Manabu Yamazaki; Satoshi Maruyama; Tatsuya AbÉ; Nyein Nyein Chan; Taiichi Kitano; Tadaharu Kobayashi; Takeyasu Maeda; Jun-Ichi Tanuma
Journal:  Oncol Lett       Date:  2022-01-11       Impact factor: 2.967

  10 in total

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