Literature DB >> 21707083

The 2010 Philip S. Portoghese Medicinal Chemistry Lectureship: addressing the "core issue" in the design of estrogen receptor ligands.

John A Katzenellenbogen1.   

Abstract

Entities:  

Mesh：

Substances：

Year:  2011        PMID： 21707083      PMCID： PMC3150643          DOI： 10.1021/jm200801h

Source DB:  PubMed          Journal:  J Med Chem        ISSN： 0022-2623            Impact factor:   7.446


× No keyword cloud information.
  86 in total

1.  Nuclear and extranuclear pathway inputs in the regulation of global gene expression by estrogen receptors.

Authors:  Zeynep Madak-Erdogan; Karen J Kieser; Sung Hoon Kim; Barry Komm; John A Katzenellenbogen; Benita S Katzenellenbogen
Journal:  Mol Endocrinol       Date:  2008-07-10

2.  ER beta: identification and characterization of a novel human estrogen receptor.

Authors:  S Mosselman; J Polman; R Dijkema
Journal:  FEBS Lett       Date:  1996-08-19       Impact factor: 4.124

Review 3.  Estrogen receptors: therapies targeted to receptor subtypes.

Authors:  S Nilsson; J-Å Gustafsson
Journal:  Clin Pharmacol Ther       Date:  2010-12-01       Impact factor: 6.875

4.  Solid-phase synthesis of tetrasubstituted pyrazoles, novel ligands for the estrogen receptor.

Authors:  S R Stauffer; J A Katzenellenbogen
Journal:  J Comb Chem       Date:  2000 Jul-Aug

5.  Acyclic amides as estrogen receptor ligands: synthesis, binding, activity and receptor interaction.

Authors:  S R Stauffer; J Sun; B S Katzenellenbogen; J A Katzenellenbogen
Journal:  Bioorg Med Chem       Date:  2000-06       Impact factor: 3.641

6.  Ring nitrogen-substituted non-steroidal estrogens: pyridine and pyrimidine analogs of the phenol in deoxyhexestrol experience resonance constraints on preferred ligand conformation.

Authors:  Meri De Angelis; John A Katzenellenbogen
Journal:  Bioorg Med Chem Lett       Date:  2004-12-06       Impact factor: 2.823

7.  Estrogen receptor (ER)-beta reduces ERalpha-regulated gene transcription, supporting a "ying yang" relationship between ERalpha and ERbeta in mice.

Authors:  Marie K Lindberg; Sofia Movérare; Stanko Skrtic; Hui Gao; Karin Dahlman-Wright; Jan-Ake Gustafsson; Claes Ohlsson
Journal:  Mol Endocrinol       Date:  2003-02

8.  Bicyclo[2.2.2]octanes: close structural mimics of the nuclear receptor-binding motif of steroid receptor coactivators.

Authors:  Hai-Bing Zhou; Margaret L Collins; Jillian R Gunther; John S Comninos; John A Katzenellenbogen
Journal:  Bioorg Med Chem Lett       Date:  2007-05-23       Impact factor: 2.823

9.  Response-specific and ligand dose-dependent modulation of estrogen receptor (ER) alpha activity by ERbeta in the uterus.

Authors:  Jonna Frasor; Daniel H Barnett; Jeanne M Danes; Rex Hess; Albert F Parlow; Benita S Katzenellenbogen
Journal:  Endocrinology       Date:  2003-07       Impact factor: 4.736

10.  Characterization of the biological roles of the estrogen receptors, ERalpha and ERbeta, in estrogen target tissues in vivo through the use of an ERalpha-selective ligand.

Authors:  Heather A Harris; John A Katzenellenbogen; Benita S Katzenellenbogen
Journal:  Endocrinology       Date:  2002-11       Impact factor: 4.736
View more
  21 in total

1.  Selenophenes: Introducing a New Element into the Core of Non-Steroidal Estrogen Receptor Ligands.

Authors:  Silong Zhang; Zhiyong Wang; Zhiye Hu; Changhao Li; Chu Tang; Kathryn E Carlson; Junjie Luo; Chune Dong; John A Katzenellenbogen; Jian Huang; Hai-Bing Zhou
Journal:  ChemMedChem       Date:  2017-01-09       Impact factor: 3.466

2.  Selective Human Estrogen Receptor Partial Agonists (ShERPAs) for Tamoxifen-Resistant Breast Cancer.

Authors:  Rui Xiong; Hitisha K Patel; Lauren M Gutgesell; Jiong Zhao; Loruhama Delgado-Rivera; Thao N D Pham; Huiping Zhao; Kathryn Carlson; Teresa Martin; John A Katzenellenbogen; Terry W Moore; Debra A Tonetti; Gregory R J Thatcher
Journal:  J Med Chem       Date:  2015-12-30       Impact factor: 7.446

3.  Adamantyl Antiestrogens with Novel Side Chains Reveal a Spectrum of Activities in Suppressing Estrogen Receptor Mediated Activities in Breast Cancer Cells.

Authors:  Jian Min; Valeria Sanabria Guillen; Abhishek Sharma; Yuechao Zhao; Yvonne Ziegler; Ping Gong; Christopher G Mayne; Sathish Srinivasan; Sung Hoon Kim; Kathryn E Carlson; Kendall W Nettles; Benita S Katzenellenbogen; John A Katzenellenbogen
Journal:  J Med Chem       Date:  2017-07-14       Impact factor: 7.446

4.  Thiophene-core estrogen receptor ligands having superagonist activity.

Authors:  Jian Min; Pengcheng Wang; Sathish Srinivasan; Jerome C Nwachukwu; Pu Guo; Minjian Huang; Kathryn E Carlson; John A Katzenellenbogen; Kendall W Nettles; Hai-Bing Zhou
Journal:  J Med Chem       Date:  2013-04-15       Impact factor: 7.446

5.  Neural-Network Scoring Functions Identify Structurally Novel Estrogen-Receptor Ligands.

Authors:  Jacob D Durrant; Kathryn E Carlson; Teresa A Martin; Tavina L Offutt; Christopher G Mayne; John A Katzenellenbogen; Rommie E Amaro
Journal:  J Chem Inf Model       Date:  2015-09-04       Impact factor: 4.956

6.  Assessment of the novel estrogen receptor PET tracer 4-fluoro-11β-methoxy-16α-[(18)F]fluoroestradiol (4FMFES) by PET imaging in a breast cancer murine model.

Authors:  Michel Paquette; Serge Phoenix; René Ouellet; Réjean Langlois; Johan E van Lier; Eric E Turcotte; Francois Bénard; Roger Lecomte
Journal:  Mol Imaging Biol       Date:  2013-10       Impact factor: 3.488

7.  Nonsteroidal bivalent estrogen ligands: an application of the bivalent concept to the estrogen receptor.

Authors:  Min Shan; Kathryn E Carlson; Alexander Bujotzek; Anja Wellner; Ronald Gust; Marcus Weber; John A Katzenellenbogen; Rainer Haag
Journal:  ACS Chem Biol       Date:  2013-01-30       Impact factor: 5.100

8.  Characterization of estrogen-receptor-targeted contrast agents in solution, breast cancer cells, and tumors in vivo.

Authors:  Adi Pais; Inbal Eti Biton; Raanan Margalit; Hadassa Degani
Journal:  Magn Reson Med       Date:  2012-08-10       Impact factor: 4.668

9.  Role of nuclear receptors in lipid dysfunction and obesity-related diseases.

Authors:  Hollie I Swanson; Taira Wada; Wen Xie; Barbara Renga; Angela Zampella; Eleonora Distrutti; Stefano Fiorucci; Bo Kong; Ann M Thomas; Grace L Guo; Ramesh Narayanan; Muralimohan Yepuru; James T Dalton; John Y L Chiang
Journal:  Drug Metab Dispos       Date:  2012-10-04       Impact factor: 3.922

10.  A trisubstituted pyrazole derivative reduces DMBA-induced mammary tumor growth in rats by inhibiting estrogen receptor-α expression.

Authors:  Hanumappa Ananda; Kothanahally S Sharath Kumar; Muddenahalli S Sudhanva; Shobith Rangappa; Kanchugarakoppal S Rangappa
Journal:  Mol Cell Biochem       Date:  2018-05-18       Impact factor: 3.396
View more

北京卡尤迪生物科技股份有限公司 © 2022-2023.