BACKGROUND: Studies have reported tracking of blood pressure (BP) from childhood to adulthood but with inconsistent results mainly due to methodological and ethnic differences. We aimed to examine BP tracking during a 7-year period in a Greek cohort. METHODS: This is a longitudinal school-based study conducted during 1990-96 in Athens, Greece. Children underwent BP and anthropometric measurements on two to three visits annually (averaged to annual values) for 7 years. RESULTS: A total of 166 children with complete yearly follow-up data for the examined period were included (mean baseline age 9 ± 1.7 years, range: 5-12 years, 89 boys). At baseline, the prevalence of pre- and hypertension was 22.9 and 24.1% respectively and at the end of the follow-up 24.1% (P = NS vs. baseline) and 13.3% (P = 0.02 vs. baseline) respectively. Systolic/diastolic BP tracking correlation coefficients between 1990 and 1996 were 0.38 (P < 0.001)/0.20 (P = 0.06) for boys and 0.30 (P = 0.007)/0.22 (P = 0.06) for girls. Among children with baseline BP ≥90th centile (systolic and/or diastolic), 44% remained in the same BP range after 7 years. In stepwise multiple regression analysis, baseline systolic BP, male gender, baseline body mass index (BMI) and change in BMI from baseline to the end of the follow-up (ΔBMI) were significant predictors of systolic BP levels at the end of the follow-up. Baseline diastolic BP, baseline BMI and ΔBMI were significant predictors of diastolic BP at the end of the follow-up. CONCLUSIONS: These data suggest that the risk of developing high BP during adolescence can be predicted by BP and BMI at childhood.
BACKGROUND: Studies have reported tracking of blood pressure (BP) from childhood to adulthood but with inconsistent results mainly due to methodological and ethnic differences. We aimed to examine BP tracking during a 7-year period in a Greek cohort. METHODS: This is a longitudinal school-based study conducted during 1990-96 in Athens, Greece. Children underwent BP and anthropometric measurements on two to three visits annually (averaged to annual values) for 7 years. RESULTS: A total of 166 children with complete yearly follow-up data for the examined period were included (mean baseline age 9 ± 1.7 years, range: 5-12 years, 89 boys). At baseline, the prevalence of pre- and hypertension was 22.9 and 24.1% respectively and at the end of the follow-up 24.1% (P = NS vs. baseline) and 13.3% (P = 0.02 vs. baseline) respectively. Systolic/diastolic BP tracking correlation coefficients between 1990 and 1996 were 0.38 (P < 0.001)/0.20 (P = 0.06) for boys and 0.30 (P = 0.007)/0.22 (P = 0.06) for girls. Among children with baseline BP ≥90th centile (systolic and/or diastolic), 44% remained in the same BP range after 7 years. In stepwise multiple regression analysis, baseline systolic BP, male gender, baseline body mass index (BMI) and change in BMI from baseline to the end of the follow-up (ΔBMI) were significant predictors of systolic BP levels at the end of the follow-up. Baseline diastolic BP, baseline BMI and ΔBMI were significant predictors of diastolic BP at the end of the follow-up. CONCLUSIONS: These data suggest that the risk of developing high BP during adolescence can be predicted by BP and BMI at childhood.
Authors: Santhi K Ganesh; Daniel I Chasman; Martin G Larson; Xiuqing Guo; Germain Verwoert; Joshua C Bis; Xiangjun Gu; Albert V Smith; Min-Lee Yang; Yan Zhang; Georg Ehret; Lynda M Rose; Shih-Jen Hwang; George J Papanicolau; Eric J Sijbrands; Kenneth Rice; Gudny Eiriksdottir; Vasyl Pihur; Paul M Ridker; Ramachandran S Vasan; Christopher Newton-Cheh; Leslie J Raffel; Najaf Amin; Jerome I Rotter; Kiang Liu; Lenore J Launer; Ming Xu; Mark Caulfield; Alanna C Morrison; Andrew D Johnson; Dhananjay Vaidya; Abbas Dehghan; Guo Li; Claude Bouchard; Tamara B Harris; He Zhang; Eric Boerwinkle; David S Siscovick; Wei Gao; Andre G Uitterlinden; Fernando Rivadeneira; Albert Hofman; Cristen J Willer; Oscar H Franco; Yong Huo; Jacqueline C M Witteman; Patricia B Munroe; Vilmundur Gudnason; Walter Palmas; Cornelia van Duijn; Myriam Fornage; Daniel Levy; Bruce M Psaty; Aravinda Chakravarti Journal: Am J Hum Genet Date: 2014-06-26 Impact factor: 11.025
Authors: Maike Wolters; Carmen Dering; Alfonso Siani; Paola Russo; Jaakko Kaprio; Patrizia Risé; Luis A Moreno; Stefaan De Henauw; Kirsten Mehlig; Toomas Veidebaum; Denés Molnár; Michael Tornaritis; Licia Iacoviello; Yannis Pitsiladis; Claudio Galli; Ronja Foraita; Claudia Börnhorst Journal: PLoS One Date: 2017-07-21 Impact factor: 3.240