OBJECTIVES: To investigate the construct validity of the commonly used 8- and 12-domain versions of the Stroke-Specific Quality of Life (SS-QOL) with a first-order factor model. The better-fitted version was further evaluated by a second-order factor structure model in order to determine whether a summary score is justified. DESIGN: Cohort study. SETTING: Outpatient stroke clinic. PARTICIPANTS: Patients (N=388) with ischemic stroke. INTERVENTION: Not applicable. MAIN OUTCOME MEASURES: The SS-QOL. We first conducted confirmatory factor analysis (CFA) to evaluate the construct validity of the first-order 8- or 12-domain versions of the SS-QOL. The better-fitted version was then validated by investigating the second-order health-related quality of life (HRQOL) factor. RESULTS: The 12-domain version, but not the 8-domain version, had sufficient goodness of fit (χ(2)=2041.7, df=1061, χ(2)/df=1.9, comparative fit index [CFI]=0.98, Tucker-Lewis index [TLI]=0.98, and root mean square error of approximation=0.05). All items of the 12-domain version showed acceptable factor loadings (>0.40) and were retained. Furthermore, the second-order CFA fit indices of the 12 domains were acceptable (χ(2)=2630.3, df=1115, χ(2)/df=2.4, CFI=0.97, TLI=0.97, root mean square error of approximation=0.06), indicating that a summary score was justified for representing the overall status of HRQOL. CONCLUSIONS: Our results show that the construct validity of the 12-domain SS-QOL is well supported for measuring HRQOL in ischemic stroke patients. Thus, we recommend the 12-domain version of the SS-QOL for use in capturing the multiple impacts of stroke as well as overall HRQOL status on the basis of patients' perspectives.
OBJECTIVES: To investigate the construct validity of the commonly used 8- and 12-domain versions of the Stroke-Specific Quality of Life (SS-QOL) with a first-order factor model. The better-fitted version was further evaluated by a second-order factor structure model in order to determine whether a summary score is justified. DESIGN: Cohort study. SETTING:Outpatientstroke clinic. PARTICIPANTS: Patients (N=388) with ischemic stroke. INTERVENTION: Not applicable. MAIN OUTCOME MEASURES: The SS-QOL. We first conducted confirmatory factor analysis (CFA) to evaluate the construct validity of the first-order 8- or 12-domain versions of the SS-QOL. The better-fitted version was then validated by investigating the second-order health-related quality of life (HRQOL) factor. RESULTS: The 12-domain version, but not the 8-domain version, had sufficient goodness of fit (χ(2)=2041.7, df=1061, χ(2)/df=1.9, comparative fit index [CFI]=0.98, Tucker-Lewis index [TLI]=0.98, and root mean square error of approximation=0.05). All items of the 12-domain version showed acceptable factor loadings (>0.40) and were retained. Furthermore, the second-order CFA fit indices of the 12 domains were acceptable (χ(2)=2630.3, df=1115, χ(2)/df=2.4, CFI=0.97, TLI=0.97, root mean square error of approximation=0.06), indicating that a summary score was justified for representing the overall status of HRQOL. CONCLUSIONS: Our results show that the construct validity of the 12-domain SS-QOL is well supported for measuring HRQOL in ischemic strokepatients. Thus, we recommend the 12-domain version of the SS-QOL for use in capturing the multiple impacts of stroke as well as overall HRQOL status on the basis of patients' perspectives.
Authors: Jennifer Wu; Lucy Dodakian; Jill See; Erin Burke Quinlan; Lisa Meng; Jeby Abraham; Ellen C Wong; Vu Le; Alison McKenzie; Steven C Cramer Journal: Neurorehabil Neural Repair Date: 2020-10-21 Impact factor: 3.919
Authors: Fernanda C da Silva; Daniela F T da Silva; Raquel A Mesquita-Ferrari; Kristianne P S Fernandes; Sandra K Bussadori Journal: J Phys Ther Sci Date: 2015-07-22
Authors: Marufat Oluyemisi Odetunde; Aderonke Omobonike Akinpelu; Adesola Christiana Odole Journal: Health Qual Life Outcomes Date: 2017-10-19 Impact factor: 3.186