Literature DB >> 21704285

Early postoperative severity of illness predicts outcomes after the stage I Norwood procedure.

John M Karamichalis1, Pedro J del Nido, Ravi R Thiagarajan, Kathy J Jenkins, Hua Liu, Kimberlee Gauvreau, Frank A Pigula, Francis E Fynn-Thompson, Sitaram M Emani, John E Mayer, Emile A Bacha.   

Abstract

BACKGROUND: We hypothesize that a measure of the immediate postoperative severity of illness after the stage I Norwood operation reflects technical performance or the adequacy of anatomic repair and can serve as a predictor of hospital mortality, reinterventions, and clinical outcomes.
METHODS: One hundred thirty-five patients undergoing stage I were retrospectively studied (2004 to 2007). The severity of illness on postoperative day 1 (POD1) was measured using the Pediatric Risk of Mortality III (PRISM) scoring system. Technical performance scores (optimal, adequate, inadequate) were calculated before hospital discharge. Hospital mortality, postoperative reinterventions, and complications were recorded. Postoperative reintervention was defined as need for cardiac catheterization laboratory or operating room based procedure that included balloon dilation or repair of arch obstruction, shunt revision, reoperations for bleeding, and extracorporeal membrane oxygenation support.
RESULTS: Hospital mortality was 14.1% (n=19). The rate of complications and reinterventions was, respectively, 28.1% (n=38) and 26.7% (n=36). The POD1 PRISM score was associated with technical performance (p=0.003). Higher POD1 PRISM scores were associated with mortality (p<0.001), complications (p<0.001), and reinterventions (p=0.001). The POD1 PRISM score had high discrimination for mortality, complications, reinterventions, and inadequate technical performance (areas under the receiver operating characteristic curve were 0.835, 0.776, 0.773, and 0.710, respectively; p≤0.001 for all).
CONCLUSIONS: The severity of illness as measured by PRISM score on POD1 after the stage I Norwood operation has strong association and discrimination with hospital mortality, postoperative reinterventions, inadequate technical performance, and major postoperative complications. It may be used as an early surrogate of technical performance to initiate a search for and correction of technical deficiencies.
Copyright © 2011 The Society of Thoracic Surgeons. Published by Elsevier Inc. All rights reserved.

Entities:  

Mesh:

Year:  2011        PMID: 21704285     DOI: 10.1016/j.athoracsur.2011.03.086

Source DB:  PubMed          Journal:  Ann Thorac Surg        ISSN: 0003-4975            Impact factor:   4.330


  5 in total

1.  Identified mortality risk factors associated with presentation, initial hospitalisation, and interstage period for the Norwood operation in a multi-centre registry: a report from the national pediatric cardiology-quality improvement collaborative.

Authors:  Russell R Cross; Ashraf S Harahsheh; Robert McCarter; Gerard R Martin
Journal:  Cardiol Young       Date:  2013-02-06       Impact factor: 1.093

2.  Technical performance score is associated with outcomes after the Norwood procedure.

Authors:  Meena Nathan; Lynn A Sleeper; Richard G Ohye; Peter C Frommelt; Christopher A Caldarone; James S Tweddell; Minmin Lu; Gail D Pearson; J William Gaynor; Christian Pizarro; Ismee A Williams; Steven D Colan; Carolyn Dunbar-Masterson; Peter J Gruber; Kevin Hill; Jennifer Hirsch-Romano; Jeffrey P Jacobs; Jonathan R Kaltman; S Ram Kumar; David Morales; Scott M Bradley; Kirk Kanter; Jane W Newburger
Journal:  J Thorac Cardiovasc Surg       Date:  2014-06-19       Impact factor: 5.209

Review 3.  Current status of the hybrid approach for the treatment of hypoplastic left heart syndrome.

Authors:  Yorikazu Harada
Journal:  Gen Thorac Cardiovasc Surg       Date:  2013-12-05

4.  Effect of acid-base balance on postoperative course in children with hypoplastic left heart syndrome after the modified Norwood procedure.

Authors:  Marcin Gładki; Tomasz Składzień; Rafał Żurek; Elżbieta Broniatowska; Elżbieta Wójcik; Janusz H Skalski
Journal:  Medicine (Baltimore)       Date:  2017-08       Impact factor: 1.889

Review 5.  A systematic review of the impact of volume of surgery and specialization in Norwood procedure.

Authors:  Dawid Pieper; Tim Mathes; Boulos Asfour
Journal:  BMC Pediatr       Date:  2014-08-06       Impact factor: 2.125

  5 in total

北京卡尤迪生物科技股份有限公司 © 2022-2023.