| Literature DB >> 21701697 |
Anna E Speers1, Benjamin F Cravatt.
Abstract
Activity-based protein profiling (ABPP) is a chemical proteomic method for functional interrogation of enzymes within complex proteomes. This Unit presents a protocol for in vitro and in vivo labeling using ABPP and Click Chemistry (CC)-ABPP probes for in-depth profiling using the Multi-dimensional Protein Identification Technology (MudPIT) analysis platform.Entities:
Year: 2009 PMID: 21701697 PMCID: PMC3119539 DOI: 10.1002/9780470559277.ch090138
Source DB: PubMed Journal: Curr Protoc Chem Biol ISSN: 2160-4762