| Literature DB >> 21699063 |
R Shegokar1, L Al Shaal, P R Mishra.
Abstract
Gene silencing by RNA interference is a rapidly growing therapeutic area for managing diseases. Despite research advances in this direction, the poor cellular uptake of synthetic small interfering RNAs is a major impediment to their clinical applications. Polymer and lipid-based systems are attractive carrier systems for delivery of siRNA and provide options for desirable engineering of carrier particles. In this review, there is a detailed discussion of RNAi delivery systems and recent advances in the field.Entities:
Mesh：
Substances：
Year: 2011 PMID： 21699063
Source DB: PubMed Journal: Pharmazie ISSN： 0031-7144 Impact factor: 1.267