Literature DB >> 2169890

Translation initiation factor-dependent extracts from Saccharomyces cerevisiae.

M Altmann1, S Blum, J Pelletier, N Sonenberg, T M Wilson, H Trachsel.   

Abstract

Translation initiation factor 4A- and 4E-dependent extracts were developed from Saccharomyces cerevisiae and used to study factor requirements for translation of individual mRNAs in vitro. Whereas all mRNAs tested required eIF-4A, mRNAs devoid of secondary structure in their 5' untranslated region did not require exogenous eIF-4E for translation. The latter included alfalfa mosaic virus RNA4, mRNA containing the untranslated region of tobacco mosaic virus RNA and mRNA containing part of the untranslated region of poliovirus RNA. Furthermore, initiation of translation on mRNAs containing part of the untranslated region of poliovirus RNA is most likely internal.

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Year:  1990        PMID： 2169890     DOI： 10.1016/0167-4781(90)90158-x

Source DB:  PubMed          Journal:  Biochim Biophys Acta        ISSN： 0006-3002


  19 in total

1.  The requirement for eukaryotic initiation factor 4A (elF4A) in translation is in direct proportion to the degree of mRNA 5' secondary structure.

Authors:  Y V Svitkin; A Pause; A Haghighat; S Pyronnet; G Witherell; G J Belsham; N Sonenberg
Journal:  RNA       Date:  2001-03       Impact factor: 4.942

2.  HSP101 functions as a specific translational regulatory protein whose activity is regulated by nutrient status.

Authors:  D R Wells; R L Tanguay; H Le; D R Gallie
Journal:  Genes Dev       Date:  1998-10-15       Impact factor: 11.361

3.  Internal initiation in Saccharomyces cerevisiae mediated by an initiator tRNA/eIF2-independent internal ribosome entry site element.

Authors:  S R Thompson; K D Gulyas; P Sarnow
Journal:  Proc Natl Acad Sci U S A       Date:  2001-10-30       Impact factor: 11.205

4.  Human eukaryotic translation initiation factor 4G (eIF4G) possesses two separate and independent binding sites for eIF4A.

Authors:  H Imataka; N Sonenberg
Journal:  Mol Cell Biol       Date:  1997-12       Impact factor: 4.272

5.  Zuotin, a DnaJ molecular chaperone, stimulates cap-independent translation in yeast.

Authors:  Santanu Raychaudhuri; Vanessa Fontanes; Rajeev Banerjee; Yana Bernavichute; Asim Dasgupta
Journal:  Biochem Biophys Res Commun       Date:  2006-10-02       Impact factor: 3.575

6.  TIF4631 and TIF4632: two yeast genes encoding the high-molecular-weight subunits of the cap-binding protein complex (eukaryotic initiation factor 4F) contain an RNA recognition motif-like sequence and carry out an essential function.

Authors:  C Goyer; M Altmann; H S Lee; A Blanc; M Deshmukh; J L Woolford; H Trachsel; N Sonenberg
Journal:  Mol Cell Biol       Date:  1993-08       Impact factor: 4.272

7.  Localization of a promoter in the putative internal ribosome entry site of the Saccharomyces cerevisiae TIF4631 gene.

Authors:  Valérie Vergé; Martin Vonlanthen; Jean-Michel Masson; Hans Trachsel; Michael Altmann
Journal:  RNA       Date:  2004-02       Impact factor: 4.942

8.  A small yeast RNA selectively inhibits internal initiation of translation programmed by poliovirus RNA: specific interaction with cellular proteins that bind to the viral 5'-untranslated region.

Authors:  S Das; P Coward; A Dasgupta
Journal:  J Virol       Date:  1994-11       Impact factor: 5.103

9.  Cap-dependent and cap-independent translation by internal initiation of mRNAs in cell extracts prepared from Saccharomyces cerevisiae.

Authors:  N Iizuka; L Najita; A Franzusoff; P Sarnow
Journal:  Mol Cell Biol       Date:  1994-11       Impact factor: 4.272

10.  The HRIGRXXR region of the DEAD box RNA helicase eukaryotic translation initiation factor 4A is required for RNA binding and ATP hydrolysis.

Authors:  A Pause; N Méthot; N Sonenberg
Journal:  Mol Cell Biol       Date:  1993-11       Impact factor: 4.272
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