Literature DB >> 21695563

Lymphoceles, lymphorrhea, and lymphedema after laparoscopic and open endometrial cancer staging.

Fabio Ghezzi1, Stefano Uccella, Antonella Cromi, Giorgio Bogani, Claudio Robba, Maurizio Serati, Pierfrancesco Bolis.   

Abstract

PURPOSE: To evaluate the incidence of lymphoceles, lymphorrhea, and lymphedema after systematic pelvic lymphadenectomy in patients who underwent laparoscopic or open abdominal staging for endometrial cancer.
METHODS: A total of 138 consecutive women who underwent systematic laparoscopic pelvic lymphadenectomy for endometrial cancer staging were compared to 123 historical control subjects staged via an open approach. Postoperative screening for lymphadenectomy-related complications by ultrasound was consistently performed.
RESULTS: The incidence of perioperative complications was lower in cases than in control subjects. Overall, lymphoceles were diagnosed in 19 (15.4%) and 2 (1.4%) patients who had open and laparoscopic staging, respectively (odds ratio 12.42; 95% confidence interval 2.82-54.55; P < 0.0001). Symptomatic lymphoceles were more frequent after open staging than after laparoscopy (P = 0.028). Lymphorrhea occurred in 1 and 4 patients after laparoscopic and open surgery (P = 0.19). No difference in the incidence of lymphedema was observed.
CONCLUSIONS: Our findings suggest that laparoscopic endometrial cancer staging is associated with a lower occurrence of both asymptomatic and symptomatic lymphoceles compared to open surgery.

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Mesh:

Year:  2011        PMID: 21695563     DOI: 10.1245/s10434-011-1854-5

Source DB:  PubMed          Journal:  Ann Surg Oncol        ISSN: 1068-9265            Impact factor:   5.344


  17 in total

1.  Lymphocele and ovarian cancer: risk factors and impact on survival.

Authors:  Tristan Gauthier; Catherine Uzan; Delphine Lefeuvre; Aminata Kane; Geoffroy Canlorbe; Fredéric Deschamps; Catherine Lhomme; Patricia Pautier; Philippe Morice; Sébastien Gouy
Journal:  Oncologist       Date:  2012-06-15

Review 2.  The incidence of postoperative symptomatic lymphocele after pelvic lymphadenectomy between abdominal and laparoscopic approach: a systemic review and meta-analysis.

Authors:  Jong Ha Hwang; Bo Wook Kim
Journal:  Surg Endosc       Date:  2022-04-25       Impact factor: 3.453

Review 3.  Management of endometrial precancers.

Authors:  Cornelia L Trimble; Michael Method; Mario Leitao; Karen Lu; Olga Ioffe; Moss Hampton; Robert Higgins; Richard Zaino; George L Mutter
Journal:  Obstet Gynecol       Date:  2012-11       Impact factor: 7.661

Review 4.  Role of pelvic and para-aortic lymphadenectomy in endometrial cancer: current evidence.

Authors:  Giorgio Bogani; Sean C Dowdy; William A Cliby; Fabio Ghezzi; Diego Rossetti; Andrea Mariani
Journal:  J Obstet Gynaecol Res       Date:  2014-02       Impact factor: 1.730

5.  Long term follow-up of a phase II trial of multimodal therapy given in a "sandwich" method for stage III, IV, and recurrent endometrial cancer.

Authors:  Michelle Glasgow; Rachel Isaksson Vogel; Jennifer Burgart; Peter Argenta; Kathryn Dusenbery; Melissa A Geller
Journal:  Gynecol Oncol Res Pract       Date:  2016-05-26

Review 6.  Lymph node assessment in endometrial cancer: towards personalized medicine.

Authors:  Fabien Vidal; Arash Rafii
Journal:  Obstet Gynecol Int       Date:  2013-09-26

7.  Bleomycin sclerotherapy for severe symptomatic and persistent pelvic lymphocele.

Authors:  Ana Sofia Fernandes; Antónia Costa; Raquel Mota; Vera Paiva
Journal:  Case Rep Obstet Gynecol       Date:  2014-07-06

8.  A collagen-fibrin patch (Tachosil®) for the prevention of symptomatic lymphoceles after pelvic lymphadenectomy in women with gynecologic malignancies: a randomized clinical trial.

Authors:  Christoph Grimm; Stephan Polterauer; Samir Helmy; David Cibula; Michal Zikan; Alexander Reinthaller; Clemens Tempfer
Journal:  BMC Cancer       Date:  2014-08-30       Impact factor: 4.430

9.  A prospective pilot study on the incidence of post-operative lymphedema in women with endometrial cancer.

Authors:  Elizabeth E Hopp; Janet L Osborne; Deborah K Schneider; Claudia J Bojar; Denise S Uyar
Journal:  Gynecol Oncol Rep       Date:  2015-12-24

Review 10.  A review of the postoperative lymphatic leakage.

Authors:  Shulan Lv; Qing Wang; Wanqiu Zhao; Lu Han; Qi Wang; Nasra Batchu; Qurat Ulain; Junkai Zou; Chao Sun; Jiang Du; Qing Song; Qiling Li
Journal:  Oncotarget       Date:  2017-04-20
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