Literature DB >> 21694595

Management and outcome of microbial anterior scleritis.

Matthew A Cunningham1, Jamie K Alexander, Alice Y Matoba, Dan B Jones, Kirk R Wilhemus.   

Abstract

PURPOSE: To evaluate the prevalence, predisposing factors, and outcomes of bacterial and fungal scleritis.
METHODS: We reviewed the clinical findings, therapeutic interventions, and visual outcomes of patients with suppurative scleral inflammation without preceding microbial keratitis who had microorganisms isolated from scleral scrapings.
DESIGN: Retrospective interventional case series.
RESULTS: Of 349 patients with scleritis diagnosed from 1999 to 2009, 6 adults (1.7%) presented with suppurative inflammation of the anterior sclera due to Pseudomonas aeruginosa (2), Streptococcus pneumoniae (2), Staphylococcus aureus (1), and Scedosporium apiospermum/Pseudallescheria boydii (1). Each had ocular surgery of the affected eye before presentation. Intraocular extension occurred in 2 eyes. After local and systemic antimicrobial therapy, all improved without evisceration or enucleation, and 4 attained vision of 20/60 or better.
CONCLUSIONS: Bacterial or fungal scleritis is an uncommon ocular infection that can belatedly follow anterior segment procedures. Antimicrobial therapy and surgical intervention can successfully control progressive suppuration and reduce vision-limiting complications.

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Year:  2011        PMID: 21694595      PMCID: PMC3154501          DOI: 10.1097/ICO.0b013e31820967bd

Source DB:  PubMed          Journal:  Cornea        ISSN: 0277-3740            Impact factor:   2.651


  27 in total

1.  Management of infectious scleritis after pterygium excision.

Authors:  F C Huang; S P Huang; S H Tseng
Journal:  Cornea       Date:  2000-01       Impact factor: 2.651

Review 2.  Scleritis.

Authors:  Narciss Okhravi; Bola Odufuwa; Peter McCluskey; Susan Lightman
Journal:  Surv Ophthalmol       Date:  2005 Jul-Aug       Impact factor: 6.048

Review 3.  Combination intravenous ceftazidime and aminoglycosides in the treatment of pseudomonal scleritis.

Authors:  C J Helm; G N Holland; R G Webster; R K Maloney; B J Mondino
Journal:  Ophthalmology       Date:  1997-05       Impact factor: 12.079

4.  Scleritis: a clinicopathologic study of 55 cases.

Authors:  W P Riono; A A Hidayat; N A Rao
Journal:  Ophthalmology       Date:  1999-07       Impact factor: 12.079

5.  Six cases of scleritis associated with systemic infection.

Authors:  R Hemady; M Sainz de la Maza; M B Raizman; C S Foster
Journal:  Am J Ophthalmol       Date:  1992-07-15       Impact factor: 5.258

6.  Prevalence of bacterial pathogens causing ocular infections in South India.

Authors:  S Ramesh; R Ramakrishnan; M Jayahar Bharathi; M Amuthan; S Viswanathan
Journal:  Indian J Pathol Microbiol       Date:  2010 Apr-Jun       Impact factor: 0.740

7.  Intrascleral dissemination of infectious scleritis following pterygium excision.

Authors:  C H Hsiao; J J Chen; S C Huang; H K Ma; P Y Chen; R J Tsai
Journal:  Br J Ophthalmol       Date:  1998-01       Impact factor: 4.638

8.  Severe corneoscleral infection. A complication of beta irradiation scleral necrosis following pterygium excision.

Authors:  A P Moriarty; G J Crawford; I L McAllister; I J Constable
Journal:  Arch Ophthalmol       Date:  1993-07

9.  Treatment of infectious scleritis and keratoscleritis.

Authors:  M G Reynolds; E Alfonso
Journal:  Am J Ophthalmol       Date:  1991-11-15       Impact factor: 5.258

10.  Activity of voriconazole against corneal isolates of Scedosporium apiospermum.

Authors:  Kekul B Shah; Tzu G Wu; Kirk R Wilhelmus; Dan B Jones
Journal:  Cornea       Date:  2003-01       Impact factor: 2.651

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  7 in total

1.  Interventions and Outcomes in Patients with Infectious Pseudomonas scleritis: A 10-Year Perspective.

Authors:  Sumayya Ahmad; Michelle Lopez; Marwan Attala; Anat Galor; Natalie A Stanciu; Darlene Miller; Leejee Suh; Thomas Albini; Victor L Perez; Carol L Karp; Janet L Davis; Eduardo Alfonso; Richard K Forster; Guillermo Amescua
Journal:  Ocul Immunol Inflamm       Date:  2017-10-17       Impact factor: 3.070

2.  Anterior infectious necrotizing scleritis secondary to Pseudomonas aeruginosa infection following intravitreal ranibizumab injection.

Authors:  Razek Georges Coussa; Susan M Wakil; Hady Saheb; David E Lederer; Karin M Oliver; Devinder P Cheema
Journal:  Am J Ophthalmol Case Rep       Date:  2016-10-29

Review 3.  Infectious Scleritis: What the ID Clinician Should Know.

Authors:  Richelle L Guerrero-Wooley; James E Peacock
Journal:  Open Forum Infect Dis       Date:  2018-06-11       Impact factor: 3.835

Review 4.  Scleritis: Differentiating infectious from non-infectious entities.

Authors:  Somasheila I Murthy; Swapnali Sabhapandit; S Balamurugan; Pranesh Subramaniam; Maite Sainz-de-la-Maza; Manisha Agarwal; Carlos Parvesio
Journal:  Indian J Ophthalmol       Date:  2020-09       Impact factor: 1.848

5.  Umbilical amnion and amniotic membrane transplantation for infectious scleritis and scleral melt: A case series.

Authors:  Zeba A Syed; Christopher J Rapuano
Journal:  Am J Ophthalmol Case Rep       Date:  2021-01-23

Review 6.  Clinical characteristics and visual outcomes in infectious scleritis: a review.

Authors:  Emeline Radhika Ramenaden; Veena Rao Raiji
Journal:  Clin Ophthalmol       Date:  2013-11-04

7.  Infectious scleritis: clinical spectrum and management outcomes in India.

Authors:  Zia Sultan Pradhan; Pushpa Jacob
Journal:  Indian J Ophthalmol       Date:  2013-10       Impact factor: 1.848

  7 in total

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