BACKGROUND:Obstructive sleep apnea (OSA) has been associated with cardiac abnormalities. Whether any cardiac dysfunction is present in ischemic stroke patients with OSA is not known. The purpose of this study was to compare echocardiographic findings in ischemic stroke patients with and without OSA. METHODS:Nocturnal polysomnography was performed on 28 ischemic stroke subjects within 7 days of symptom onset. OSA was defined as an apnea-hypopnea index of ≥10. Echocardiographic variables were compared between the OSA and non OSA groups using Wilcoxon signed-rank, chi-square, or Fisher's exact tests. RESULTS: The 14 (50%) subjects with OSA had comparable cardiac function and structure to those without OSA (n=14). Left ventricular (LV) mass index, LV ejection fraction, LV diastolic function, left atrial area, and right ventricular systolic function were not different between groups. Ischemic stroke subjects, regardless of their OSA status, had LV diastolic dysfunction with preserved systolic function. CONCLUSIONS: Subjects with and without OSA, based on polysomnography in the first 7 days after stroke, have comparable right and left ventricular function.
RCT Entities:
BACKGROUND:Obstructive sleep apnea (OSA) has been associated with cardiac abnormalities. Whether any cardiac dysfunction is present in ischemic strokepatients with OSA is not known. The purpose of this study was to compare echocardiographic findings in ischemic strokepatients with and without OSA. METHODS: Nocturnal polysomnography was performed on 28 ischemic stroke subjects within 7 days of symptom onset. OSA was defined as an apnea-hypopnea index of ≥10. Echocardiographic variables were compared between the OSA and non OSA groups using Wilcoxon signed-rank, chi-square, or Fisher's exact tests. RESULTS: The 14 (50%) subjects with OSA had comparable cardiac function and structure to those without OSA (n=14). Left ventricular (LV) mass index, LV ejection fraction, LV diastolic function, left atrial area, and right ventricular systolic function were not different between groups. Ischemic stroke subjects, regardless of their OSA status, had LV diastolic dysfunction with preserved systolic function. CONCLUSIONS: Subjects with and without OSA, based on polysomnography in the first 7 days after stroke, have comparable right and left ventricular function.
Authors: Shun Kohsaka; Robert R Sciacca; Kenichi Sugioka; Ralph L Sacco; Shunichi Homma; Marco R Di Tullio Journal: Stroke Date: 2005-10-06 Impact factor: 7.914
Authors: Devin L Brown; J Rajiv Bapuraj; Suresh K Mukherji; Ronald D Chervin; Maryann Concannon; Joseph I Helman; Lynda D Lisabeth Journal: Sleep Med Date: 2010-05-13 Impact factor: 3.492
Authors: Marion E Barnes; Yoko Miyasaka; James B Seward; Bernard J Gersh; A Gabriela Rosales; Kent R Bailey; George W Petty; David O Wiebers; Teresa S M Tsang Journal: Mayo Clin Proc Date: 2004-08 Impact factor: 7.616
Authors: Melissa C Lipford; Kelly D Flemming; Andrew D Calvin; Jay Mandrekar; Robert D Brown; Virend K Somers; Sean M Caples Journal: Sleep Date: 2015-11-01 Impact factor: 5.849