Literature DB >> 2168993

Transcriptional analysis of the eight-kilobase mRNA encoding the major capsid protein of human cytomegalovirus.

S A Rudolph1, T Stamminger, G Jahn.   

Abstract

The 8-kilobase mRNA coding for the major capsid protein (MCP) of human cytomegalovirus was precisely mapped. Two 5' ends of the transcript were located within HindIII fragment a, 29 and 34 base pairs, respectively, downstream of the sequence TATTAGA. The 3' end was localized within HindIII fragment b of the viral genome. The MCP transcript was synthesized at late times after infection and was not detected before viral DNA replication. In addition, the MCP promoter region could be identified, which strongly responded to viral trans activation at early and late times after infection in a transient expression assay.

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Year:  1990        PMID： 2168993      PMCID： PMC248011          DOI： 10.1128/JVI.64.10.5167-5172.1990

Source DB:  PubMed          Journal:  J Virol        ISSN： 0022-538X            Impact factor:   5.103


  19 in total

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Authors:  S H McDonough; D H Spector
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5.  Characterization of a major late herpes simplex virus type 1 mRNA.

Authors:  R H Costa; B G Devi; K P Anderson; B H Gaylord; E K Wagner
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6.  Human cytomegalovirus DNA: restriction enzyme cleavage maps and map locations for immediate-early, early, and late RNAs.

Authors:  J M Demarchi
Journal:  Virology       Date:  1981-10-15       Impact factor: 3.616

7.  Temporal patterns of human cytomegalovirus transcription: mapping the viral RNAs synthesized at immediate early, early, and late times after infection.

Authors:  M W Wathen; M F Stinski
Journal:  J Virol       Date:  1982-02       Impact factor: 5.103

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Authors:  R H Costa; G Cohen; R Eisenberg; D Long; E Wagner
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  7 in total

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Authors:  Rebecca L Sanders; Christia J Del Rosario; Elizabeth A White; Deborah H Spector
Journal:  J Virol       Date:  2008-09-10       Impact factor: 5.103

2.  A mutation deleting sequences encoding the amino terminus of human cytomegalovirus UL84 impairs interaction with UL44 and capsid localization.

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3.  Alternate promoter selection within a human cytomegalovirus immediate-early and early transcription unit (UL119-115) defines true late transcripts containing open reading frames for putative viral glycoproteins.

Authors:  M P Leatham; P R Witte; M F Stinski
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Authors:  D J Tenney; G Yamanaka; S M Voss; C W Cianci; A V Tuomari; A K Sheaffer; M Alam; R J Colonno
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Authors:  M Winkler; S A Rice; T Stamminger
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6.  An inducible promoter mediates abundant expression from the immediate-early 2 gene region of human cytomegalovirus at late times after infection.

Authors:  E Puchtler; T Stamminger
Journal:  J Virol       Date:  1991-11       Impact factor: 5.103

7.  Human cytomegalovirus UL36-38 and US3 immediate-early genes: temporally regulated expression of nuclear, cytoplasmic, and polysome-associated transcripts during infection.

Authors:  D J Tenney; A M Colberg-Poley
Journal:  J Virol       Date:  1991-12       Impact factor: 5.103
  7 in total

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