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Literature DB >> 21686250

A novel pseudo-complementary PNA G-C base pair.

Anne G Olsen¹, Otto Dahl, Asger B Petersen, John Nielsen, Peter E Nielsen.

Abstract

Pseudo-complementary oligonucleotide analogues and mimics provide novel opportunities for targeting duplex structures in RNA and DNA. Previously, a pseudo-complementary A-T base pair has been introduced. Towards sequence unrestricted targeting, a pseudo-complementary G-C base pair consisting of the unnatural nucleobases n6-methoxy-2,6-diaminopurine (previously described in a DNA context) and N4-benzoylcytosine is now presented for design of pseudo-complementary PNA oligomers (pcPNAs).

Entities: Chemical

Year: 2011 PMID： 21686250 PMCID： PMC3116581 DOI： 10.4161/adna.2.1.15554

Source DB: PubMed Journal: Artif DNA PNA XNA ISSN： 1949-095X

15 in total

1. Double duplex invasion by peptide nucleic acid: a general principle for sequence-specific targeting of double-stranded DNA.

Authors: J Lohse; O Dahl; P E Nielsen
Journal: Proc Natl Acad Sci U S A Date: 1999-10-12 Impact factor: 11.205

2. Sequence-specific protection of duplex DNA against restriction and methylation enzymes by pseudocomplementary PNAs.

Authors: K I Izvolsky; V V Demidov; P E Nielsen; M D Frank-Kamenetskii
Journal: Biochemistry Date: 2000-09-05 Impact factor: 3.162

3. Pseudocomplementary PNAs as selective modifiers of protein activity on duplex DNA: the case of type IIs restriction enzymes.

Authors: Ekaterina Protozanova; Vadim V Demidov; Peter E Nielsen; Maxim D Frank-Kamenetskii
Journal: Nucleic Acids Res Date: 2003-07-15 Impact factor: 16.971

4. Origin of high fidelity in target-sequence recognition by PNA-Ce(IV)/EDTA combinations as site-selective DNA cutters.

Authors: Yoshitaka Miyajima; Takumi Ishizuka; Yoji Yamamoto; Jun Sumaoka; Makoto Komiyama
Journal: J Am Chem Soc Date: 2009-02-25 Impact factor: 15.419

Review 5. Artificial restriction DNA cutters as new tools for gene manipulation.

Authors: Hitoshi Katada; Makoto Komiyama
Journal: Chembiochem Date: 2009-05-25 Impact factor: 3.164

6. Site-selective scission of human genome by artificial restriction DNA cutter.

Authors: Kenichiro Ito; Hitoshi Katada; Narumi Shigi; Makoto Komiyama
Journal: Chem Commun (Camb) Date: 2009-09-08 Impact factor: 6.222

7. Inhibition of PNA triplex formation by N4-benzoylated cytosine.

Authors: L Christensen; H F Hansen; T Koch; P E Nielsen
Journal: Nucleic Acids Res Date: 1998-06-01 Impact factor: 16.971

8. Unrestricted accessibility of short oligonucleotides to RNA.

Authors: Howard B Gamper; Khalil Arar; Alan Gewirtz; Ya-Ming Hou
Journal: RNA Date: 2005-09 Impact factor: 4.942

9. Synthesis and duplex stability of oligonucleotides containing adenine-guanine analogues.

Authors: D M Brown; P K Lin
Journal: Carbohydr Res Date: 1991-09-02 Impact factor: 2.104

10. Targeted correction of a thalassemia-associated beta-globin mutation induced by pseudo-complementary peptide nucleic acids.

Authors: Pallavi Lonkar; Ki-Hyun Kim; Jean Y Kuan; Joanna Y Chin; Faye A Rogers; Melissa P Knauert; Ryszard Kole; Peter E Nielsen; Peter M Glazer
Journal: Nucleic Acids Res Date: 2009-04-13 Impact factor: 16.971

3 in total

Review 1. Chemical modifications of artificial restriction DNA cutter (ARCUT) to promote its in vivo and in vitro applications.

Authors: Makoto Komiyama
Journal: Artif DNA PNA XNA Date: 2014-12-15

Review 2. Antibacterial Peptide Nucleic Acids-Facts and Perspectives.

Authors: Monika Wojciechowska; Marcin Równicki; Adam Mieczkowski; Joanna Miszkiewicz; Joanna Trylska
Journal: Molecules Date: 2020-01-28 Impact factor: 4.411

Review 3. Peptide nucleic acids: Advanced tools for biomedical applications.

Authors: Anjali Gupta; Anuradha Mishra; Nidhi Puri
Journal: J Biotechnol Date: 2017-07-29 Impact factor: 3.307

3 in total