Literature DB >> 216782

Concentration of homovanillic acid and 5-hydroxyindoleacetic acid in the ventricular cerebrospinal fluid of patients with obstructive hydrocephalus.

K Kmieciak-Kolada, H Majchrzak, Z S Herman.   

Abstract

In 12 patients with different posterior fossa tumours the concentrations of homovanillic acid (HVA) and of 5-hydroxyindoleacetic acid (5-HIAA) were measured in cerebrospinal fluid from the lateral ventricles. All patients had obstructive hydrocephalus. Patients with a clear increase of 5-HIAA/HVA ratio in the ventricular CSF have died subsequently. This feature may have a diagnostic value, and indicates the prevalence of serotoninergic neurones in patients with obstructive hydrocephalus with fatal course after surgery.

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Year:  1979        PMID： 216782      PMCID： PMC490163          DOI： 10.1136/jnnp.42.1.78

Source DB:  PubMed          Journal:  J Neurol Neurosurg Psychiatry        ISSN： 0022-3050            Impact factor:   10.154


  13 in total

1.  On the occurrence of homovanillic acid in brain and cerebrospinal fluid and its determination by a fluorometric method.

Authors:  N E ANDEN; B E ROOS; B WERDINIUS
Journal:  Life Sci (1962)       Date:  1963-07

Review 2.  Monoamine metabolites in lumbar CSF: the question of their origin in relation to clinical studies.

Authors:  E Garelis; S N Young; S Lal; T L Sourkes
Journal:  Brain Res       Date:  1974-10-11       Impact factor: 3.252

3.  Norepinephrine metabolism in the central nervous system of man: studies using 3-methoxy-4-hydroxyphenylethylene glycol levels in cerebrospinal fluid.

Authors:  T N Chase; E K Gordon; L K Ng
Journal:  J Neurochem       Date:  1973-09       Impact factor: 5.372

4.  Comparative effects of p-chloroamphetamine and p-chloro-N-methylamphetamine on rat brain norepinephrine, serotonin and 5-hydroxyindole-3-acetic acid.

Authors:  F P Miller; R H Cox; W R Snodgrass; R P Maickel
Journal:  Biochem Pharmacol       Date:  1970-02       Impact factor: 5.858

Review 5.  Cerebral metabolites in cerebrospinal fluid as a biochemical approach to the brain.

Authors:  A T Moir; G W Ashcroft; T B Crawford; D Eccleston; H C Guldberg
Journal:  Brain       Date:  1970       Impact factor: 13.501

6.  Dopamine metabolites in human brain.

Authors:  S Wilk; M Stanley
Journal:  Psychopharmacology (Berl)       Date:  1978-04-14       Impact factor: 4.530

7.  Increased level of 5-hydroxyindoleacetic acid in cerebrospinal fluid from infantile hydrocephalus.

Authors:  H Andersson; B E Roos
Journal:  Experientia       Date:  1966-08-15

8.  Homovanillic acid and 5-hydroxyindole-acetic acid in the csf of patients after a severe head injury. II. Ventricular csf concentrations in acute brain post-traumatic syndromes.

Authors:  M Porta; S R Bareggi; M Collice; B M Assael; A Selenati; G Calderini; M Rossanda; P L Morselli
Journal:  Eur Neurol       Date:  1975       Impact factor: 1.710

9.  Concentration gradients of monoamine metabolites in human cerebrospinal fluid.

Authors:  R Sjöström; J Ekstedt; E Anggård
Journal:  J Neurol Neurosurg Psychiatry       Date:  1975-07       Impact factor: 10.154

10.  Monoamine acid metabolites and cerebrospinal fluid dynamics in normal pressure hydrocephalus: preliminary results.

Authors:  G Maira; S R Bareggi; C Di Rocco; G Calderini; P L Morselli
Journal:  J Neurol Neurosurg Psychiatry       Date:  1975-02       Impact factor: 10.154
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