Literature DB >> 21677914

Monomorphic ventricular tachycardia caused by arsenic trioxide therapy for acute promyelocytic leukaemia.

R A Ducas1, M D Seftel, J Ducas, C Seifer.   

Abstract

Arsenic trioxide has become the treatment of choice for patients with acute promyelocytic leukaemia. Cardiovascular toxicity is known to occur with this therapy, in particular heart rhythm disorders due to QT interval prolongation. We present a case of ventricular arrhythmia with no QT prolongation in a patient receiving arsenic trioxide therapy.

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Year:  2011        PMID： 21677914     DOI： 10.4997/JRCPE.2011.204

Source DB:  PubMed          Journal:  J R Coll Physicians Edinb        ISSN： 1478-2715


  7 in total

1.  Potential Protective Effect of Spirulina Platensis on Sodium Arsenite Induced Cardiotoxicity in Male Rats.

Authors:  Amal Albtoosh; Fardous Karawya; Wesam Al-Naymat; Aiman Al-Qaitat
Journal:  Tissue Barriers       Date:  2021-10-06

2.  Arsenic trioxide and resveratrol show synergistic anti-leukemia activity and neutralized cardiotoxicity.

Authors:  Yuhua Fan; Meng Chen; Jia Meng; Lei Yu; Yingfeng Tu; Lin Wan; Kun Fang; Wenliang Zhu
Journal:  PLoS One       Date:  2014-08-21       Impact factor: 3.240

Review 3.  Antioxidants Protect against Arsenic Induced Mitochondrial Cardio-Toxicity.

Authors:  Clare Pace; Ruben Dagda; Jeff Angermann
Journal:  Toxics       Date:  2017-12-05

4.  Synergistic inhibition of leukemia WEHI-3 cell growth by arsenic trioxide and Hedyotis diffusa Willd extract in vitro and in vivo.

Authors:  Yu-Jui Kuo; Yan-Jin Liu; Tzong-Der Way; Su-Yin Chiang; Jaung-Geng Lin; Jing-Gung Chung
Journal:  Exp Ther Med       Date:  2017-04-27       Impact factor: 2.447

5.  QT Independent Ventricular Tachycardia Induced by Arsenic Trioxide.

Authors:  Vicken Zeitjian; Carmel Moazez; Waqas Arslan; Mehrdad Saririan
Journal:  Case Rep Cardiol       Date:  2019-10-13

Review 6.  Toward a broader view of mechanisms of drug cardiotoxicity.

Authors:  Polina Mamoshina; Blanca Rodriguez; Alfonso Bueno-Orovio
Journal:  Cell Rep Med       Date:  2021-03-16

7.  L-Ascorbic Acid and α-Tocopherol Synergistically Triggers Apoptosis Inducing Antileukemic Effects of Arsenic Trioxide via Oxidative Stress in Human Acute Promyelocytic Leukemia Cells.

Authors:  Radhakrishnan Chandraprabha Vineetha; Sreedharan Hariharan; Abdul Jaleel; Mahesh Chandran; Raveendran Harikumaran Nair
Journal:  Front Oncol       Date:  2020-02-21       Impact factor: 6.244
  7 in total

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