OBJECTIVES: To conduct a study to determine whether weight changes were associated with the risk of developing lower urinary tract symptoms (LUTS). Obesity has been associated with LUTS in aging men. METHODS: The study population consisted of men participating in the Olmsted County Study of Urinary Symptoms and Health Status among Men and the Flint Men's Health Study. Weight loss and weight gain were defined as a change of ≥5% of the baseline weight. LUTS progression was measured by calculating the American Urological Association Symptom Index (AUASI) score slopes for 4 years of follow-up in both cohorts. Additional Cox proportional hazard models were constructed to determine whether the weight changes were associated with the later development of moderate-to-severe symptoms or with a ≥4-point increase in the AUASI score (Olmsted County Study of Urinary Symptoms and Health Status among Men cohort only). RESULTS: Weight changes were not associated with LUTS progression (all P > .05). Additionally, the rate at which the AUASI scores changed did not vary by the weight change. Finally, in the Olmsted County Study of Urinary Symptoms and Health Status among Men cohort, the weight changes were not associated with risk of having a moderate-to-severe AUASI score or a ≥4-point increase in the AUASI score. CONCLUSIONS: Modest weight loss might not prevent the onset or progression of LUTS. However, modest weight gain also might not contribute to changes in LUTS.
OBJECTIVES: To conduct a study to determine whether weight changes were associated with the risk of developing lower urinary tract symptoms (LUTS). Obesity has been associated with LUTS in aging men. METHODS: The study population consisted of men participating in the Olmsted County Study of Urinary Symptoms and Health Status among Men and the Flint Men's Health Study. Weight loss and weight gain were defined as a change of ≥5% of the baseline weight. LUTS progression was measured by calculating the American Urological Association Symptom Index (AUASI) score slopes for 4 years of follow-up in both cohorts. Additional Cox proportional hazard models were constructed to determine whether the weight changes were associated with the later development of moderate-to-severe symptoms or with a ≥4-point increase in the AUASI score (Olmsted County Study of Urinary Symptoms and Health Status among Men cohort only). RESULTS: Weight changes were not associated with LUTS progression (all P > .05). Additionally, the rate at which the AUASI scores changed did not vary by the weight change. Finally, in the Olmsted County Study of Urinary Symptoms and Health Status among Men cohort, the weight changes were not associated with risk of having a moderate-to-severe AUASI score or a ≥4-point increase in the AUASI score. CONCLUSIONS: Modest weight loss might not prevent the onset or progression of LUTS. However, modest weight gain also might not contribute to changes in LUTS.
Authors: S G Heeringa; K H Alcser; K Doerr; M Strawderman; K Cooney; B Medbery; D Schottenfeld Journal: J Clin Epidemiol Date: 2001-02 Impact factor: 6.437
Authors: C J Girman; S J Jacobsen; T Tsukamoto; F Richard; W M Garraway; P P Sagnier; H A Guess; T Rhodes; P Boyle; M M Lieber Journal: Urology Date: 1998-03 Impact factor: 2.649
Authors: J Kellogg Parsons; H Ballentine Carter; Alan W Partin; B Gwen Windham; E Jeffrey Metter; Luigi Ferrucci; Patricia Landis; Elizabeth A Platz Journal: J Clin Endocrinol Metab Date: 2006-04-11 Impact factor: 5.958
Authors: Joseph E Donnelly; Steven N Blair; John M Jakicic; Melinda M Manore; Janet W Rankin; Bryan K Smith Journal: Med Sci Sports Exerc Date: 2009-02 Impact factor: 5.411
Authors: E Giovannucci; E B Rimm; C G Chute; I Kawachi; G A Colditz; M J Stampfer; W C Willett Journal: Am J Epidemiol Date: 1994-12-01 Impact factor: 4.897
Authors: Scott R Bauer; Stephanie L Harrison; Peggy M Cawthon; Angela Senders; Stacey A Kenfield; Anne M Suskind; Charles E McCulloch; Kenneth Covinsky; Lynn M Marshall Journal: J Gerontol A Biol Sci Med Sci Date: 2022-10-06 Impact factor: 6.591
Authors: Benjamin N Breyer; Suzanne Phelan; Patricia E Hogan; Raymond C Rosen; Abbas E Kitabchi; Rena R Wing; Jeanette S Brown Journal: J Urol Date: 2014-02-14 Impact factor: 7.450
Authors: Aruna V Sarma; Jennifer L St Sauver; Debra J Jacobson; Michaela E McGree; George G Klee; Michael M Lieber; Cynthia J Girman; John M Hollingsworth; Steven J Jacobsen Journal: Urology Date: 2013-10-16 Impact factor: 2.649
Authors: Lisa J Moran; Grant D Brinkworth; Sean Martin; Thomas P Wycherley; Bronwyn Stuckey; Janna Lutze; Peter M Clifton; Gary A Wittert; Manny Noakes Journal: PLoS One Date: 2016-09-01 Impact factor: 3.240