| Literature DB >> 21670803 |
Jia Lin Huang1, Michael E Noss, Karson M Schmidt, Leigh Murray, Michelle R Bunagan.
Abstract
Using circular dichroism spectroscopy, we show evidence of unusual folding behaviour for several designed peptides in neat ionic liquid. Helical peptides, AKA(2) and Trp-cage, exhibit heat-induced folding, with stable helical structure persisting to 96 °C, whereas the β-hairpin Trpzip4 is destabilized by the neat [C(4)mpy][Tf(2)N].Entities:
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Year: 2011 PMID： 21670803 DOI： 10.1039/c1cc11527h
Source DB: PubMed Journal: Chem Commun (Camb) ISSN： 1359-7345 Impact factor: 6.222