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Literature DB >> 21670181

Pharmacokinetics/pharmacodynamics of colistin and imipenem on mucoid and nonmucoid Pseudomonas aeruginosa biofilms.

Wang Hengzhuang¹, Hong Wu, Oana Ciofu, Zhijun Song, Niels Høiby.

Abstract

The time course of activity of colistin and imipenem against mucoid and nonmucoid Pseudomonas aeruginosa growing in a biofilm showed that compared with those for planktonic bacteria, the kinetics of colistin and imipenem retained the concentration- and time-dependent killing, respectively, but higher doses of antibiotics and longer dosing periods were required for biofilm eradication. Biofilms of mucoid P. aeruginosa were more difficult to eradicate than nonmucoid biofilms.

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Year: 2011 PMID： 21670181 PMCID： PMC3165294 DOI： 10.1128/AAC.00126-11

Source DB: PubMed Journal: Antimicrob Agents Chemother ISSN： 0066-4804 Impact factor: 5.191

38 in total

Review 1. Riddle of biofilm resistance.

Authors: K Lewis
Journal: Antimicrob Agents Chemother Date: 2001-04 Impact factor: 5.191

Review 2. Pseudomonas aeruginosa and the in vitro and in vivo biofilm mode of growth.

Authors: N Høiby; H Krogh Johansen; C Moser; Z Song; O Ciofu; A Kharazmi
Journal: Microbes Infect Date: 2001-01 Impact factor: 2.700

Review 3. Animal model pharmacokinetics and pharmacodynamics: a critical review.

Authors: D Andes; W A Craig
Journal: Int J Antimicrob Agents Date: 2002-04 Impact factor: 5.283

4. Determination of minimum inhibitory concentrations.

Authors: J M Andrews
Journal: J Antimicrob Chemother Date: 2001-07 Impact factor: 5.790

5. Detection of N-acylhomoserine lactones in lung tissues of mice infected with Pseudomonas aeruginosa.

Authors: H Wu; Z Song; M Hentzer; J B Andersen; A Heydorn; K Mathee; C Moser; L Eberl; S Molin; N Høiby; M Givskov
Journal: Microbiology Date: 2000-10 Impact factor: 2.777

Review 6. Mechanisms of biofilm resistance to antimicrobial agents.

Authors: T F Mah; G A O'Toole
Journal: Trends Microbiol Date: 2001-01 Impact factor: 17.079

Review 7. Antibiotic therapy against Pseudomonas aeruginosa in cystic fibrosis: a European consensus.

Authors: G Döring; S P Conway; H G Heijerman; M E Hodson; N Høiby; A Smyth; D J Touw
Journal: Eur Respir J Date: 2000-10 Impact factor: 16.671

8. Constitutive high expression of chromosomal beta-lactamase in Pseudomonas aeruginosa caused by a new insertion sequence (IS1669) located in ampD.

Authors: Niels Bagge; Oana Ciofu; Morten Hentzer; Joan I A Campbell; Michael Givskov; Niels Høiby
Journal: Antimicrob Agents Chemother Date: 2002-11 Impact factor: 5.191

9. Alginate overproduction affects Pseudomonas aeruginosa biofilm structure and function.

Authors: M Hentzer; G M Teitzel; G J Balzer; A Heydorn; S Molin; M Givskov; M R Parsek
Journal: J Bacteriol Date: 2001-09 Impact factor: 3.490

Review 10. Biofilms: survival mechanisms of clinically relevant microorganisms.

Authors: Rodney M Donlan; J William Costerton
Journal: Clin Microbiol Rev Date: 2002-04 Impact factor: 26.132

70 in total

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Authors: Thomas Bjarnsholt; Oana Ciofu; Søren Molin; Michael Givskov; Niels Høiby
Journal: Nat Rev Drug Discov Date: 2013-10 Impact factor: 84.694

Review 2. Pharmacokinetic and Pharmacodynamic Optimization of Antibiotic Therapy in Cystic Fibrosis Patients: Current Evidences, Gaps in Knowledge and Future Directions.

Authors: Charlotte Roy; Manon Launay; Sophie Magréault; Isabelle Sermet-Gaudelus; Vincent Jullien
Journal: Clin Pharmacokinet Date: 2021-01-24 Impact factor: 6.447

3. Luminescent Nanosensors for Ratiometric Monitoring of Three-Dimensional Oxygen Gradients in Laboratory and Clinical Pseudomonas aeruginosa Biofilms.

Authors: Megan P Jewell; Anne A Galyean; J Kirk Harris; Edith T Zemanick; Kevin J Cash
Journal: Appl Environ Microbiol Date: 2019-10-01 Impact factor: 4.792

Pharmacokinetics/pharmacodynamics of colistin and imipenem on mucoid and nonmucoid Pseudomonas aeruginosa biofilms.

Review 1. Riddle of biofilm resistance.

Review 2. Pseudomonas aeruginosa and the in vitro and in vivo biofilm mode of growth.

Review 3. Animal model pharmacokinetics and pharmacodynamics: a critical review.

4. Determination of minimum inhibitory concentrations.

5. Detection of N-acylhomoserine lactones in lung tissues of mice infected with Pseudomonas aeruginosa.

Review 6. Mechanisms of biofilm resistance to antimicrobial agents.

Review 7. Antibiotic therapy against Pseudomonas aeruginosa in cystic fibrosis: a European consensus.

8. Constitutive high expression of chromosomal beta-lactamase in Pseudomonas aeruginosa caused by a new insertion sequence (IS1669) located in ampD.

9. Alginate overproduction affects Pseudomonas aeruginosa biofilm structure and function.

Review 10. Biofilms: survival mechanisms of clinically relevant microorganisms.

Review 1. Applying insights from biofilm biology to drug development - can a new approach be developed?

Review 2. Pharmacokinetic and Pharmacodynamic Optimization of Antibiotic Therapy in Cystic Fibrosis Patients: Current Evidences, Gaps in Knowledge and Future Directions.

3. Luminescent Nanosensors for Ratiometric Monitoring of Three-Dimensional Oxygen Gradients in Laboratory and Clinical Pseudomonas aeruginosa Biofilms.

Review 4. Pseudomonas aeruginosa AmpR: an acute-chronic switch regulator.

5. Breaking the Vicious Cycle of Antibiotic Killing and Regrowth of Biofilm-Residing Pseudomonas aeruginosa.

6. A New Tool to Reveal Bacterial Signaling Mechanisms in Antibiotic Treatment and Resistance.

Review 7. Bacterial Extracellular Polysaccharides in Biofilm Formation and Function.

Review 8. Rescuing the Last-Line Polymyxins: Achievements and Challenges.

9. Effect of bacteriocin and exopolysaccharides isolated from probiotic on P. aeruginosa PAO1 biofilm.

10. Tryptophan inhibits biofilm formation by Pseudomonas aeruginosa.