| Literature DB >> 11226851 |
N Høiby1, H Krogh Johansen, C Moser, Z Song, O Ciofu, A Kharazmi.
Abstract
The biofilm mode of growth is the survival strategy of environmental bacteria like Pseudomonas aeruginosa. Such P. aeruginosa biofilms also occur in the lungs of chronically infected cystic fibrosis patients, where they protect the bacteria against antibiotics and the immune response. The lung tissue damage is due to immune complex mediated chronic inflammation dominated by polymorphonuclear leukocytes releasing proteases and oxygen radicals.Entities:
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Year: 2001 PMID: 11226851 DOI: 10.1016/s1286-4579(00)01349-6
Source DB: PubMed Journal: Microbes Infect ISSN: 1286-4579 Impact factor: 2.700