OBJECTIVES: To investigate whether KALRN gene variation is associated with ischemic stroke (IS). DESIGN AND METHODS: Associations to overall IS and IS subtypes were investigated in SAHLSIS, which comprises 844 patients with IS and 668 controls. RESULTS: Associations between KALRN SNPs and overall IS and cardioembolic stroke were detected. Associations for overall IS were investigated in two additional Swedish samples, but could not be replicated. CONCLUSION: KALRN gene variation is not associated with overall IS.
OBJECTIVES: To investigate whether KALRN gene variation is associated with ischemic stroke (IS). DESIGN AND METHODS: Associations to overall IS and IS subtypes were investigated in SAHLSIS, which comprises 844 patients with IS and 668 controls. RESULTS: Associations between KALRN SNPs and overall IS and cardioembolic stroke were detected. Associations for overall IS were investigated in two additional Swedish samples, but could not be replicated. CONCLUSION:KALRN gene variation is not associated with overall IS.
Authors: Håkan Lövkvist; Sandra Olsson; Peter Höglund; Olle Melander; Christina Jern; Marketa Sjögren; Gunnar Engström; J Gustav Smith; Bo Hedblad; Gunnar Andsberg; Hossein Delavaran; Katarina Jood; Ulf Kristoffersson; Holger Luthman; Bo Norrving; Arne Lindgren Journal: Eur J Hum Genet Date: 2012-01-25 Impact factor: 4.246
Authors: Cavin Ward-Caviness; Carol Haynes; Colette Blach; Elaine Dowdy; Simon G Gregory; Svati H Shah; Benjamin D Horne; William E Kraus; Elizabeth R Hauser Journal: Hum Genet Date: 2013-08-02 Impact factor: 4.132