| Literature DB >> 21663788 |
Stuart M Chambers1, Lorenz Studer.
Abstract
Building on the discovery that MyoD expression reprograms fibroblasts into muscle, three papers (Vierbuchen et al., 2010; Ieda et al., 2010; Szabo et al., 2010) recently reported the reprogramming of fibroblasts into neurons, cardiomyocytes, and blood cell progenitors without first passing the cells through a pluripotent state. Here we discuss the advantages and challenges of harnessing this direct reprogramming method for regenerative medicine.Entities:
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Year: 2011 PMID： 21663788 DOI： 10.1016/j.cell.2011.05.036
Source DB: PubMed Journal: Cell ISSN： 0092-8674 Impact factor: 41.582