| Literature DB >> 21653769 |
Zdenek Novak1, Nazma Chowdhury, Shannon A Ross, Sunil K Pati, Karen Fowler, Suresh B Boppana.
Abstract
Failure of a cytomegalovirus (CMV) real-time PCR assay targeting glycoprotein B (gB) was investigated. A multiplex assay targeting gB and immediate-early 2 (IE2) genes showed discordant results (gB negative and IE positive or a >10-fold-higher viral load with IE primers) in saliva from 14.6% of CMV-infected newborns. Sequencing revealed 3 patterns of gB variations.Entities:
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Year: 2011 PMID: 21653769 PMCID: PMC3147759 DOI: 10.1128/JCM.01039-11
Source DB: PubMed Journal: J Clin Microbiol ISSN: 0095-1137 Impact factor: 5.948