| Literature DB >> 2165201 |
Abstract
Replication and recombination structures can be interconverted by branch-migration. Using this simple concept a novel mechanism is proposed for generating concatemers through an initial single-strand DNA invasion into a duplex. Only DNAs with terminal repeats can form concatemers, and Herpes Simplex Virus DNA replication is considered in detail. The model is more parsimonious than other models such as Watson's for concatemer formation.Mesh:
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Year: 1990 PMID: 2165201 DOI: 10.1016/s0022-5193(05)80318-2
Source DB: PubMed Journal: J Theor Biol ISSN: 0022-5193 Impact factor: 2.691