| Literature DB >> 21643476 |
Abstract
We present a simple influence function based approach to compute the variances of estimates of absolute risk and functions of absolute risk. We apply this approach to criteria that assess the impact of changes in the risk factor distribution on absolute risk for an individual and at the population level. As an illustration we use an absolute risk prediction model for breast cancer that includes modifiable risk factors in addition to standard breast cancer risk factors. Influence function based variance estimates for absolute risk and the criteria are compared to bootstrap variance estimates.Entities:
Year: 2011 PMID: 21643476 PMCID: PMC3105901 DOI: 10.1016/j.spl.2011.02.002
Source DB: PubMed Journal: Stat Probab Lett ISSN: 0167-7152 Impact factor: 0.870