Literature DB >> 21642509

Multiple roles of Ypd1 phosphotransfer protein in viability, stress response, and virulence factor regulation in Cryptococcus neoformans.

Jang-Won Lee1, Young-Joon Ko, Seo-Young Kim, Yong-Sun Bahn.   

Abstract

Ypd1 is a key phosphorelay protein that controls eukaryotic two-component systems, but its function in Cryptococcus neoformans is not known. Here, we report that Ypd1 is required for the viability of C. neoformans via the Hog1 mitogen-activated protein kinase (MAPK) pathway but plays multiple cellular roles in both a Hog1-dependent and -independent manner.

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Year:  2011        PMID： 21642509      PMCID： PMC3147412          DOI： 10.1128/EC.05124-11

Source DB:  PubMed          Journal:  Eukaryot Cell        ISSN： 1535-9786


  24 in total

Review 1.  Two-component signal transduction pathways in Arabidopsis.

Authors:  Ildoo Hwang; Huei-Chi Chen; Jen Sheen
Journal:  Plant Physiol       Date:  2002-06       Impact factor: 8.340

2.  Insights into eukaryotic multistep phosphorelay signal transduction revealed by the crystal structure of Ypd1p from Saccharomyces cerevisiae.

Authors:  H K Song; J Y Lee; M G Lee; J Moon; K Min; J K Yang; S W Suh
Journal:  J Mol Biol       Date:  1999-11-05       Impact factor: 5.469

3.  Ssk1p response regulator binding surface on histidine-containing phosphotransfer protein Ypd1p.

Authors:  Stace W Porter; Qingping Xu; Ann H West
Journal:  Eukaryot Cell       Date:  2003-02

4.  Spy1, a histidine-containing phosphotransfer signaling protein, regulates the fission yeast cell cycle through the Mcs4 response regulator.

Authors:  K Aoyama; Y Mitsubayashi; H Aiba; T Mizuno
Journal:  J Bacteriol       Date:  2000-09       Impact factor: 3.490

5.  Comparative transcriptome analysis of the CO2 sensing pathway via differential expression of carbonic anhydrase in Cryptococcus neoformans.

Authors:  Min Su Kim; Young-Joon Ko; Shinae Maeng; Anna Floyd; Joseph Heitman; Yong-Sun Bahn
Journal:  Genetics       Date:  2010-06-01       Impact factor: 4.562

6.  Yeast HOG1 MAP kinase cascade is regulated by a multistep phosphorelay mechanism in the SLN1-YPD1-SSK1 "two-component" osmosensor.

Authors:  F Posas; S M Wurgler-Murphy; T Maeda; E A Witten; T C Thai; H Saito
Journal:  Cell       Date:  1996-09-20       Impact factor: 41.582

7.  A PCR-based strategy to generate integrative targeting alleles with large regions of homology.

Authors:  Robert C Davidson; Jill R Blankenship; Peter R Kraus; Marisol de Jesus Berrios; Christina M Hull; Cletus D'Souza; Ping Wang; Joseph Heitman
Journal:  Microbiology       Date:  2002-08       Impact factor: 2.777

8.  An efficiently regulated promoter system for Cryptococcus neoformans utilizing the CTR4 promoter.

Authors:  Jeramia J Ory; Cara L Griffith; Tamara L Doering
Journal:  Yeast       Date:  2004-08       Impact factor: 3.239

9.  Initiation of sporulation in B. subtilis is controlled by a multicomponent phosphorelay.

Authors:  D Burbulys; K A Trach; J A Hoch
Journal:  Cell       Date:  1991-02-08       Impact factor: 41.582

10.  Saccharomyces cerevisiae histidine phosphotransferase Ypd1p shuttles between the nucleus and cytoplasm for SLN1-dependent phosphorylation of Ssk1p and Skn7p.

Authors:  Jade Mei-Yeh Lu; Robert J Deschenes; Jan S Fassler
Journal:  Eukaryot Cell       Date:  2003-12
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  23 in total

Review 1.  The yeasts phosphorelay systems: a comparative view.

Authors:  Griselda Salas-Delgado; Laura Ongay-Larios; Laura Kawasaki-Watanabe; Imelda López-Villaseñor; Roberto Coria
Journal:  World J Microbiol Biotechnol       Date:  2017-05-03       Impact factor: 3.312

2.  Two-component histidine phosphotransfer protein Ypd1 is not essential for viability in Candida albicans.

Authors:  John Mavrianos; Chirayu Desai; Neeraj Chauhan
Journal:  Eukaryot Cell       Date:  2014-01-31

Review 3.  Stress signaling pathways for the pathogenicity of Cryptococcus.

Authors:  Yong-Sun Bahn; Kwang-Woo Jung
Journal:  Eukaryot Cell       Date:  2013-09-27

4.  A flucytosine-responsive Mbp1/Swi4-like protein, Mbs1, plays pleiotropic roles in antifungal drug resistance, stress response, and virulence of Cryptococcus neoformans.

Authors:  Min-Hee Song; Jang-Won Lee; Min Su Kim; Ja-Kyung Yoon; Theodore C White; Anna Floyd; Joseph Heitman; Anna K Strain; Judith N Nielsen; Kirsten Nielsen; Yong-Sun Bahn
Journal:  Eukaryot Cell       Date:  2011-11-11

Review 5.  The Cryptococcus neoformans capsule: a sword and a shield.

Authors:  Teresa R O'Meara; J Andrew Alspaugh
Journal:  Clin Microbiol Rev       Date:  2012-07       Impact factor: 26.132

Review 6.  Histidine phosphotransfer proteins in fungal two-component signal transduction pathways.

Authors:  Jan S Fassler; Ann H West
Journal:  Eukaryot Cell       Date:  2013-06-14

7.  Distinct and redundant roles of protein tyrosine phosphatases Ptp1 and Ptp2 in governing the differentiation and pathogenicity of Cryptococcus neoformans.

Authors:  Kyung-Tae Lee; Hyo-Jeong Byun; Kwang-Woo Jung; Joohyeon Hong; Eunji Cheong; Yong-Sun Bahn
Journal:  Eukaryot Cell       Date:  2014-04-11

8.  The phosphorelay signal transduction system in Candida glabrata: an in silico analysis.

Authors:  Natalee Carapia-Minero; Juan Arturo Castelán-Vega; Néstor Octavio Pérez; Aída Verónica Rodríguez-Tovar
Journal:  J Mol Model       Date:  2017-12-16       Impact factor: 1.810

9.  Essential roles of the Kar2/BiP molecular chaperone downstream of the UPR pathway in Cryptococcus neoformans.

Authors:  Kwang-Woo Jung; Hyun Ah Kang; Yong-Sun Bahn
Journal:  PLoS One       Date:  2013-03-06       Impact factor: 3.240

Review 10.  The two-component signal transduction system and its regulation in Candida albicans.

Authors:  Binyou Liao; Xingchen Ye; Xi Chen; Yujie Zhou; Lei Cheng; Xuedong Zhou; Biao Ren
Journal:  Virulence       Date:  2021-12       Impact factor: 5.882
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