Literature DB >> 2163812

Factors of importance when evaluating quality of life in clinical trials.

I Wiklund1, E Dimenäs, M Wahl.   

Abstract

Quality of life (QoL) has during recent years become recognized as an important outcome in clinical trials. But it is not sufficient just to incorporate QoL measures in a trial. Several factors have important repercussions on the results of clinical trials using QoL as an outcome measure. Unless more attention is directed towards factors that may be important when evaluating QoL, the value of including these measurements in clinical trials will be minimized. Important issues pertain to trial design, duration of follow-up, the role of placebo effects, side effects, and confounding variables.

Mesh：

Year:  1990        PMID： 2163812     DOI： 10.1016/0197-2456(90)90011-p

Source DB:  PubMed          Journal:  Control Clin Trials        ISSN： 0197-2456


  17 in total

1.  Aspects of quality of life on treatment with felodipine.

Authors:  E Dimenäs; M A Wallander; K Svärdsudd; I Wiklund
Journal:  Eur J Clin Pharmacol       Date:  1991       Impact factor: 2.953

2.  Myotonic dystrophy health index: Correlations with clinical tests and patient function.

Authors:  Chad Heatwole; Rita Bode; Nicholas E Johnson; Jeanne Dekdebrun; Nuran Dilek; Katy Eichinger; James E Hilbert; Eric Logigian; Elizabeth Luebbe; William Martens; Michael P Mcdermott; Shree Pandya; Araya Puwanant; Nan Rothrock; Charles Thornton; Barbara G Vickrey; David Victorson; Richard T Moxley
Journal:  Muscle Nerve       Date:  2015-12-29       Impact factor: 3.217

3.  Visual and non-visual factors associated with patient satisfaction and quality of life in LASIK.

Authors:  P Lazon de la Jara; D Erickson; P Erickson; F Stapleton
Journal:  Eye (Lond)       Date:  2011-07-01       Impact factor: 3.775

Review 4.  Quality-of-life measurements in the evaluation of treatment: proposed guidelines.

Authors:  A Fletcher
Journal:  Br J Clin Pharmacol       Date:  1995-03       Impact factor: 4.335

Review 5.  Patient reported outcomes in gastroesophageal reflux disease: an overview of available measures.

Authors:  Nicholas J Talley; Ingela Wiklund
Journal:  Qual Life Res       Date:  2005-02       Impact factor: 4.147

Review 6.  Does exercise training augment improvements in quality of life induced by energy restriction for obese populations? A systematic review.

Authors:  Daniel J van den Hoek; Clint T Miller; Steve F Fraser; Steve E Selig; John B Dixon
Journal:  Qual Life Res       Date:  2017-05-27       Impact factor: 4.147

Review 7.  Symptom evaluation in reflux disease: workshop background, processes, terminology, recommendations, and discussion outputs.

Authors:  J Dent; D Armstrong; B Delaney; P Moayyedi; N J Talley; N Vakil
Journal:  Gut       Date:  2004-05       Impact factor: 23.059

8.  Patient-identified disease burden in facioscapulohumeral muscular dystrophy.

Authors:  Nicholas E Johnson; Christine Quinn; Eileen Eastwood; Rabi Tawil; Chad R Heatwole
Journal:  Muscle Nerve       Date:  2012-12       Impact factor: 3.217

9.  Quality-of-life in Charcot-Marie-Tooth disease: the patient's perspective.

Authors:  Nicholas E Johnson; Chad R Heatwole; Nuran Dilek; Janet Sowden; Callyn A Kirk; Denise Shereff; Michael E Shy; David N Herrmann
Journal:  Neuromuscul Disord       Date:  2014-06-27       Impact factor: 4.296

10.  Effects of 12 weeks of ramipril treatment on the quality of life in patients with moderate congestive heart failure: results of a placebo-controlled trial. Ramipril Study Group.

Authors:  T Gundersen; I Wiklund; K Swedberg; O Amtorp; J Remes; B Nilsson
Journal:  Cardiovasc Drugs Ther       Date:  1995-08       Impact factor: 3.727
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