Literature DB >> 21629275

The future of direct-to-consumer clinical genetic tests.

Felix W Frueh1, Henry T Greely, Robert C Green, Stuart Hogarth, Sue Siegel.   

Abstract

In light of the meeting of the US Food and Drug Administration (FDA) in March 2011 to discuss the regulation of clinical direct-to-consumer (DTC) genetic tests, we have invited five experts to consider the best means of overseeing the ordering and interpretation of these tests. Should these tests be regulated? If so, who, if anyone, should communicate results to consumers?

Entities:  

Mesh：

Year:  2011        PMID： 21629275      PMCID： PMC3763708          DOI： 10.1038/nrg3026

Source DB:  PubMed          Journal:  Nat Rev Genet        ISSN： 1471-0056            Impact factor:   53.242


  17 in total

1.  Genetic testing oversight.

Authors:  Kathy L Hudson
Journal:  Science       Date:  2006-09-29       Impact factor: 47.728

2.  A common variant on chromosome 9p21 affects the risk of myocardial infarction.

Authors:  Anna Helgadottir; Gudmar Thorleifsson; Andrei Manolescu; Solveig Gretarsdottir; Thorarinn Blondal; Aslaug Jonasdottir; Adalbjorg Jonasdottir; Asgeir Sigurdsson; Adam Baker; Arnar Palsson; Gisli Masson; Daniel F Gudbjartsson; Kristinn P Magnusson; Karl Andersen; Allan I Levey; Valgerdur M Backman; Sigurborg Matthiasdottir; Thorbjorg Jonsdottir; Stefan Palsson; Helga Einarsdottir; Steinunn Gunnarsdottir; Arnaldur Gylfason; Viola Vaccarino; W Craig Hooper; Muredach P Reilly; Christopher B Granger; Harland Austin; Daniel J Rader; Svati H Shah; Arshed A Quyyumi; Jeffrey R Gulcher; Gudmundur Thorgeirsson; Unnur Thorsteinsdottir; Augustine Kong; Kari Stefansson
Journal:  Science       Date:  2007-05-03       Impact factor: 47.728

3.  Effect of direct-to-consumer genomewide profiling to assess disease risk.

Authors:  Cinnamon S Bloss; Nicholas J Schork; Eric J Topol
Journal:  N Engl J Med       Date:  2011-01-12       Impact factor: 91.245

4.  Prediction of coronary heart disease using risk factor categories.

Authors:  P W Wilson; R B D'Agostino; D Levy; A M Belanger; H Silbershatz; W B Kannel
Journal:  Circulation       Date:  1998-05-12       Impact factor: 29.690

5.  Genetic testing for Alzheimer's disease and its impact on insurance purchasing behavior.

Authors:  Cathleen D Zick; Charles J Mathews; J Scott Roberts; Robert Cook-Deegan; Robert J Pokorski; Robert C Green
Journal:  Health Aff (Millwood)       Date:  2005 Mar-Apr       Impact factor: 6.301

6.  A coronary heart disease risk score based on patient-reported information.

Authors:  Arch G Mainous; Richelle J Koopman; Vanessa A Diaz; Charles J Everett; Peter W F Wilson; Barbara C Tilley
Journal:  Am J Cardiol       Date:  2007-03-13       Impact factor: 2.778

7.  Disclosure of APOE genotype for risk of Alzheimer's disease.

Authors:  Robert C Green; J Scott Roberts; L Adrienne Cupples; Norman R Relkin; Peter J Whitehouse; Tamsen Brown; Susan LaRusse Eckert; Melissa Butson; A Dessa Sadovnick; Kimberly A Quaid; Clara Chen; Robert Cook-Deegan; Lindsay A Farrer
Journal:  N Engl J Med       Date:  2009-07-16       Impact factor: 91.245

8.  An unwelcome side effect of direct-to-consumer personal genome testing: raiding the medical commons.

Authors:  Amy L McGuire; Wylie Burke
Journal:  JAMA       Date:  2008-12-10       Impact factor: 56.272

9.  Direct to consumer genetic testing: Avoiding a culture war.

Authors:  James P Evans; Robert C Green
Journal:  Genet Med       Date:  2009-08       Impact factor: 8.822

10.  Genomewide association analysis of coronary artery disease.

Authors:  Nilesh J Samani; Jeanette Erdmann; Alistair S Hall; Christian Hengstenberg; Massimo Mangino; Bjoern Mayer; Richard J Dixon; Thomas Meitinger; Peter Braund; H-Erich Wichmann; Jennifer H Barrett; Inke R König; Suzanne E Stevens; Silke Szymczak; David-Alexandre Tregouet; Mark M Iles; Friedrich Pahlke; Helen Pollard; Wolfgang Lieb; Francois Cambien; Marcus Fischer; Willem Ouwehand; Stefan Blankenberg; Anthony J Balmforth; Andrea Baessler; Stephen G Ball; Tim M Strom; Ingrid Braenne; Christian Gieger; Panos Deloukas; Martin D Tobin; Andreas Ziegler; John R Thompson; Heribert Schunkert
Journal:  N Engl J Med       Date:  2007-07-18       Impact factor: 91.245
View more
  23 in total

1.  Communication about DTC testing: commentary on a 'family experience of personal genomics'.

Authors:  Anna Middleton
Journal:  J Genet Couns       Date:  2012-01-06       Impact factor: 2.537

2.  Risky business: risk perception and the use of medical services among customers of DTC personal genetic testing.

Authors:  David J Kaufman; Juli M Bollinger; Rachel L Dvoskin; Joan A Scott
Journal:  J Genet Couns       Date:  2012-01-26       Impact factor: 2.537

Review 3.  Direct-to-consumer personalized genomic testing.

Authors:  Cinnamon S Bloss; Burcu F Darst; Eric J Topol; Nicholas J Schork
Journal:  Hum Mol Genet       Date:  2011-08-09       Impact factor: 6.150

4.  Attitudes about regulation among direct-to-consumer genetic testing customers.

Authors:  Juli Murphy Bollinger; Robert C Green; David Kaufman
Journal:  Genet Test Mol Biomarkers       Date:  2013-04-06

5.  Management of incidental findings in clinical genomic sequencing.

Authors:  Joel B Krier; Robert C Green
Journal:  Curr Protoc Hum Genet       Date:  2013

6.  Minding the aging brain: are we ready for personalized medicine?

Authors:  Jason Karlawish; Robert C Green
Journal:  Am J Psychiatry       Date:  2014-02       Impact factor: 18.112

7.  Implications of Personal Genomic Testing for Health Behaviors: The Case of Smoking.

Authors:  Emily Olfson; Sarah Hartz; Deanna Alexis Carere; Robert C Green; J Scott Roberts; Laura J Bierut
Journal:  Nicotine Tob Res       Date:  2016-07-12       Impact factor: 4.244

8.  Direct-to-Consumer Genetic Testing and Personal Genomics Services: A Review of Recent Empirical Studies.

Authors:  J Scott Roberts; Jenny Ostergren
Journal:  Curr Genet Med Rep       Date:  2013-09

9.  How Well Do Customers of Direct-to-Consumer Personal Genomic Testing Services Comprehend Genetic Test Results? Findings from the Impact of Personal Genomics Study.

Authors:  Jenny E Ostergren; Michele C Gornick; Deanna Alexis Carere; Sarah S Kalia; Wendy R Uhlmann; Mack T Ruffin; Joanna L Mountain; Robert C Green; J Scott Roberts
Journal:  Public Health Genomics       Date:  2015-06-16       Impact factor: 2.000

10.  Public Awareness of Direct-to-Consumer Genetic Tests: Findings from the 2013 U.S. Health Information National Trends Survey.

Authors:  Tanya Agurs-Collins; Rebecca Ferrer; Allison Ottenbacher; Erika A Waters; Mary E O'Connell; Jada G Hamilton
Journal:  J Cancer Educ       Date:  2015-12       Impact factor: 2.037
View more

北京卡尤迪生物科技股份有限公司 © 2022-2023.